Postdoctoral Research Associate - Genetics

Position Summary

The laboratories of Dr. Jeff Milbrandt and Dr. Rob Mitra invite highly motivated candidates to apply for positions as joint postdoctoral fellows in the Department of Genetics and McDonnell Genome Institute at WashU in St. Louis. These fellows will develop research programs in Personalized Medicine aimed at revealing the pathogenic mechanisms of disease-associated variants via monitoring phenotypic changes of genetically perturbed iPSC-derived neurons and glia.

Our collaborative, multidisciplinary group studies the mechanistic basis of genetic abnormalities that result in neurodevelopmental, neuropsychiatric, or neurodegenerative disorders, with particular emphasis on the role of mitochondrial dysfunction and metabolic deficits in disease progression. To address these questions, we use a novel multi-omics approach that integrates high-throughput imaging and machine learning methods with CRISPR/Cas9 screens and saturation mutagenesis to answer central questions about the pathophysiology that results from genetic mutations in mitochondrial proteins, chromatin regulators, and metabolic enzymes.

We interpret our experiments in the context of curated clinical phenotypes and validate key findings using banked patient samples.

This opportunity requires the ability to visit St. Louis for potential interviews.

• Information on being a postdoc at WashU in St. Louis can be found at (Use the "Apply for this Job" box below)..
• For more information on the lab please visit .

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Required Qualifications

• Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

Certifications / Professional Licenses

• No specific certification/professional license is required for this position.

Work Experience

• No specific work experience is required for this position.

Skills

• Not Applicable

Driver's License

• A driver's license is not required for this position.

Preferred Qualifications

• Ph.D. or M.D./Ph.D. in biological sciences or related fields.

Education

• No additional education unless stated elsewhere in the job posting.

Certifications / Professional Licenses

• No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience

• No additional work experience unless stated elsewhere in the job posting.

Skills

• Analytical Thinking, Communication, Genomics, Molecular Biology, Neurodegenerative Diseases, Python (Programming Language), R Programming

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

If you are unable to use our online application system and would like an accommodation, please email Candidate Questions or call the dedicated accommodation inquiry number at  and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at…