IT Systems Engineer

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late‑stage biotechnology company redefining the transplant process by developing next‑generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.

With our purified, high‑precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

As an IT Systems Admin at Orca Bio, reporting into our IT Manager, you will take on the responsibility of building, supporting, maintaining, and optimizing the IT infrastructure on premise and in the cloud.

To thrive, you must possess a strong technical foundation across systems and cloud platforms, along with a proactive, problem‑solving mindset. You should be comfortable automating routine tasks, and driving improvements through scalable, secure, and reliable solutions. Excellent communication and collaboration skills are essential as you’ll be working cross‑functionally to support fast‑paced research, development, and production environments. A strong sense of ownership, adaptability, and a passion for continuous learning will set you apart.

• Plan, deploy, and configure servers, storage systems, networks, cloud applications, and other IT infrastructure components to meet organizational needs.
• Ensure systems are running optimally by conducting maintenance, applying updates and patches, and monitoring system performance and availability.
• Diagnose and resolve hardware, software, and network issues. Provide Tier 2/3 technical support to end‑users and IT Helpdesk staff.
• Implement and maintain security protocols, including firewalls, antivirus solutions, and intrusion detection systems. Perform regular security audits and vulnerability assessments.
• Develop scripts and tools to automate tasks, improve system performance, and enhance operational efficiency.
• Maintain detailed documentation of system configurations, changes, and processes. Generate reports on system performance, usage, and incidents.
• Work closely with cross‑functional teams to align IT systems with business goals, support projects, and ensure seamless integration of new technologies.

• Bachelor’s Degree in Computer Science, Management Information Systems, or equivalent experience.
• A minimum of 3+ years of IT Systems Administration experience.
• Experience with corporate data/knowledge management.
• Location:
  
  This is an in‑office position, based at our production facility in Sacramento. Travel may be required to Menlo Park (headquarters) from time to time as needed.

• Experience working in biotech, healthcare or another highly regulated environment.
• Advanced knowledge of Microsoft 365 including Entra , Exchange Online, Intune, SharePoint Online.
• Mobile device management (MDM) experience.
• Working knowledge of administering on premise virtual environments.
• Experience with enterprise backups, replication, and disaster recovery.
• Experience with configuring, modifying, and troubleshooting Okta Application Integrations.
• Working knowledge of infrastructure automation and management.
• Experience with setup, administration, and maintenance of NAS/SAN storage arrays.
• Experience with managing enterprise firewalls, networking equipment, and wireless access points spanning multiple physical locations, subnets, and VLANs.
• General knowledge of programming principles and comfort with using common scripting languages such as Python, and Power Shell.
• General understanding of system integration approaches and requirements.

$80,000 - $125,000 a year. The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job‑related factors as permitted by law. For remote‑based positions, this range may vary based on your local market. You will also be…