Senior Scientist Job Ridgefield area,Connecticut USA,Research/Development

Job Description :

Pay Range: $50.5hr - $53.5hr

The Scientist IV will design, develop, and execute advanced functional genomics assays to support research initiatives.
This role requires deep expertise in CRISPR technologies, next-generation sequencing, and single-cell platforms, along with the ability to guide team members, maintain data integrity, and contribute to scientific innovation in a collaborative research environment.

Duties and Responsibilities:

Design, develop, and execute functional genomics assays including CRISPR-based editing such as RNP delivery and Perturb-seq, single-cell sequencing, spatial transcriptomics, and CITE-seq.
Provide technical guidance and training to research scientists on functional genomics technologies, assay execution, and troubleshooting.
Document and maintain detailed laboratory records in accordance with internal policies.
Operate and maintain laboratory equipment in collaboration with team members.
Assist with acquisition of necessary laboratory supplies and equipment.
Define and perform appropriate quality control measures.
Stay current with scientific literature to apply optimal methods and emerging best practices.
Interpret experimental outcomes, propose follow-up experiments, and suggest new research directions.
Communicate work effectively through oral presentations and written documentation including protocols and technical reports.
Automate data processing and results reporting where applicable.
Handle and report data with a high level of integrity and ethical standards.

Required Skills:

Hands-on experience designing CRISPR guides, performing transfections or infections, selecting edited cells, and validating knockouts or knock-ins.
Hands-on experience in next-generation sequencing library preparation.
Personal experience with single-cell technologies including sample preparation, library generation, and quality control.
Proficiency in standard molecular biology techniques including qPCR, Western blotting, cloning, and gel electrophoresis.
Strong cell culture experience including maintenance of multiple cell lines, transfections, and sterile technique.
Ability to perform multiple functional genomics experimental techniques simultaneously.
Demonstrated experience working in a multidisciplinary and collaborative research environment.
Ability to troubleshoot functional genomics experiments independently and within a team.
Excellent oral and written communication skills with a commitment to transparency and consistency.

Preferred Skills:

Education:

Ph.D. or Master s degree from an accredited institution in molecular biology, cell biology, or a related scientific discipline with six or more years of relevant experience.


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