Senior Director, Compliance

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Senior Director, Compliance will provide enterprise-wide compliance leadership and support across Revolution Medicines, frequently interacting with and providing compliance advice to Commercialization, Clinical, Manufacturing, Research and Development, and all corporate (G&A) functions.

The Senior Director, Compliance will support the Vice President, Compliance to implement and continuously enhance a comprehensive compliance program that spans healthcare, research, manufacturing, export controls, economic sanctions, trade and tariff-related compliance, general corporate compliance and other global business conduct requirements applicable to a growing multinational organization.

Reporting to the Vice President, Compliance, this individual will serve as a trusted advisor to senior leaders and cross-functional teams, embedding compliance into daily operations while supporting the company’s growth as commercial stage oncology organization.

• Support the VP, Compliance in maintaining the Compliance Committee and integrating the compliance program into all business operations, including Commercialization, Research and Development, G&A functions (Finance, HR, IT, Procurement, and Facilities).
• Provide compliance oversight and advisory support for general corporate risk areas, including conflicts of interest, third-party risk management, anti-bribery and corruption, data privacy, records management, and ethical business practices.
• Partner with Finance, HR, IT, and other corporate stakeholders to identify, assess, and mitigate enterprise compliance risks.
• Provide guidance on export control laws and regulations (including Export Administration Regulations (EAR) and Office of Foreign Assets Control (OFAC) requirements), sanctions list screening, and trade compliance considerations related to cross-border activities, research collaborations, technology transfers, and supply chain operations.
• Partner with Supply Chain, Manufacturing, IT, and Research teams to identify and mitigate risks related to tariffs, customs classifications, import/export restrictions, and international shipping of materials, data, and technology.
• Support development and implementation of policies, procedures, and controls related to trade compliance, including restricted party screening, license determinations, and escalation processes.
• Provide compliance guidance and oversight to Clinical Development, Clinical Operations, Manufacturing, Quality, Supply Chain, Biomedical Discovery and Early Discovery functions.
• Support Quality and Regulatory departments with compliance related to GxP environments, including GCP, GMP, and GLP activities.
• Advise Research & Development departments on compliance considerations related to research collaborations, investigator engagements, material transfers, data integrity, and third-party relationships.
• Support compliance risk assessments and monitoring activities across preclinical research, clinical trials, and manufacturing operations.
• Provide compliance support for Commercial, Marketing, Medical Affairs, Market Access, and Regulatory Affairs on matters including FDA regulations, Anti-Kickback Statute, False Claims Act, OIG guidance, Sunshine Act, and industry codes.
• Ensure alignment between healthcare compliance requirements and broader corporate compliance controls.
• Support the VP, Compliance in the development and continuous enhancement of a risk-based, effective enterprise compliance program aligned with DOJ guidance and industry best practices.
• Establish, update, and enforce compliance policies, procedures, standards,…