Scientist​/Sr. Scientist - Analytical Development

Syst Immune is a leading and well‑funded clinical‑stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies, and antibody‑drug conjugates (ADCs). With multiple assets in various stages of clinical trials for solid tumor and hematologic indications and a robust preclinical pipeline, Syst Immune offers an opportunity for you to learn and grow while making significant contributions to the company’s success.

Analytical Development Scientist /Sr. Scientist – a core contributor to the development and characterization of antibody‑based therapeutics. The scientist will design and implement analytical methods for early‑ to mid‑stage development, with a focus on UPLC, CE, and binding assays, and will also contribute to early‑stage protein formulation development work. This is a hands‑on lab role ideal for a PhD‑level scientist who thrives in a dynamic, high‑throughput setting and is proficient in cross‑functional collaboration.

The position is full‑time and onsite at our Redmond, WA location.

• Develop and execute robust analytical methods using UPLC (SEC, IEX, RP), CE (CE‑SDS, cIEF), and binding assays (ELISA, BLI) to support antibody characterization. Maintain good documentation for all studies.
• Support cell line development, process development, formulation screening, comparability, and stability studies.
• Analyze, interpret, and communicate data to project teams in a timely and scientifically rigorous manner.
• Collaborate with upstream, downstream, and formulation scientists in an integrated CMC environment.
• Author high‑quality technical reports, method protocols, and contribute to regulatory documentation.
• Evaluate new analytical technologies and help build internal capabilities as the company scales.
• Contribute to establishing a phase‑appropriate analytical control strategy for lead candidates.
• Wear multiple hats, bring solutions, and help shape the analytical infrastructure as the company grows.

• PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline.
• 0–3+ years of relevant industry experience (biotech/pharma) in biologics analytical development and strong teamwork skills.
• Solid understanding of antibody structure, post‑translational modifications, and critical quality attributes (CQAs).
• Comfortable working in a dynamic environment with shifting priorities and evolving needs.
• Excellent communication, organization, and problem‑solving skills.

• Hands‑on experience with antibody binding assays (e.g., ELISA, SPR or BLI).
• Strong technical background in HPLC/UPLC and CE techniques for therapeutic proteins.
• Experience in tech transfer, method qualification, or early GMP readiness.
• Familiarity with software platforms like JMP, Empower, Soft Max Pro, or Forte Bio Data Analysis.
• Passion for working in a mission‑driven environment and building from the ground up.

The expected base salary range for this position is $90,000 – $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications,
level of the position
, experience, and skills.

While most offers typically fall within the low to mid‑point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceed the requirements of the role.

Syst Immune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and more.

Syst Immune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.