Accounting Manager, Accounts Payable

Overview

Syst Immune is a leading and well‑funded clinical‑stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies and antibody‑drug conjugates (ADCs). Syst Immune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications and a robust preclinical pipeline of potential cancer therapeutics in the discover and IND‑enabling stages.

Accounting Manager to oversee Accounts Payable, treasury and operational accounting activities. Owns all cash‑related and transactional processes, ensuring timely execution, strong internal controls and compliance with GAAP and company policies.

• Oversee and manage the Accounts Payable function, ensuring timely and accurate processing of vendor invoices, employee reimbursements and other disbursements.
• Review and approve AP transactions, expense reimbursements, payment runs and vendor setup and registration in both banking system and Procurement system.
• Ensure compliance with internal controls, approval matrices and company policies.
• Coordinate closely with Procurement to align purchasing activity, payment terms and contract compliance.
• Resolve complex invoice discrepancies and serve as escalation point for AP issues.
• Enhance the ERP system for AP.
• Credit card management and booking.
• Support month‑end financial reporting by providing accurate AP aging report, AP by vendor and accrual list.
• Support month‑end and year‑end close related to AP and treasury, including accruals, prepaid expenses and cash‑related journal entries.
• Ensure compliance with SOX and internal control requirements, audit standards and financial policies.
• Assist with internal and external audit requests related to AP, cash and treasury.
• Manage cash disbursements including ACH, wire transfers and international payments.
• Lead treasury operations, including daily cash reporting and cash flow forecasting.
• Monitor bank accounts, perform and review bank reconciliations and investigate discrepancies; archive documentations related to banking systems.
• Manage relationships with banks and financial institutions, including account maintenance, signatory updates and fee reviews.
• Oversee intercompany payments, funding and settlement processes with proper documentation and timely execution.
• Participate in BvA analysis to analyze and monitor cash movement.
• Identify and implement process improvements to enhance efficiency, accuracy and internal controls across AP and treasury.
• Maintain and improve standard operating procedures for AP and treasury.
• Manage, mentor and develop AP staff, providing oversight, feedback and prioritization.

• Bachelor's degree in accounting, finance or related field.
• 6+ years of progressive accounting experience with ownership of AP and treasury functions.
• Strong knowledge of GAAP, internal controls and audit requirements.
• Ability to operate in a fast‑paced, growth‑stage environment.
• Fluency in Mandarin and English is required.

• CPA or CPA‑track.
• Experience with international vendors, cross‑border payments and intercompany transactions.
• Prior experience in biotech, biopharma, pharmaceutical or life sciences.
• Experience with ERP systems, SAP, Net Suite.

• High‑impact role safeguarding cash and scaling financial operations.
• Exposure to complex, R&D‑driven spend in a clinical‑stage biotech.
• Collaborative environment with visibility and ownership.

The expected base salary range for this position is $100,000 – $125,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience and skills.

Syst Immune offers a comprehensive benefits package including 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays.

Syst Immune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.