Fractional CFO

💼 Biotech IPO & Public-Markets Experience Required

📍 North Reading, MA (Hybrid / On-site as needed)

🧬 Clinical-Stage Biotechnology | Capital Markets | Executive Leadership

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Job Code: APH-2601-01

Aphios Corporation is a clinical-stage biotechnology company advancing differentiated nanotechnology platforms and next-generation therapeutics across oncology, neurodegenerative disease, infectious disease, and substance-use disorder.

As the company enters its next phase of growth and capital-markets readiness
, Aphios is seeking an experienced Part-Time / Fractional Chief Financial Officer (CFO) with direct biotech IPO and public-company preparation experience to work closely with the CEO and Board.

This role is designed for a senior biotech finance executive who has successfully guided companies through IPO preparation, public-company readiness, and alternative public-market pathways
, and who is interested in a high-impact, flexible leadership engagement rather thanوقالت full-time operating role.

• Lead financial strategy, capital planning, and cash-flow management for a growth-stage biotech
• Prepare the company for IPO and public-company readiness
  , including internal controls, reporting infrastructure, and governance
• Oversee GAAP-compliant financial reporting, audit readiness, ಅಭ risk management
• Develop and maintain long-range financial models aligned with clinical, regulatory, and commercialization milestones
• Support investor relations
  , Board communications, and external stakeholder engagement
• Structure and evaluate PIPE financings, crossover fund participation, and late-stage private capital strategies
• Advise on NASDAQ and NYSE uplisting requirements Bene ? and readiness timelines
• Evaluate SPAC or de-SPAC-adjacent opportunities
  , as appropriate, without over-engineering the business
• Interface with investment banks, auditors, securities counsel, and regulatory advisors
• Oversee grant accounting and compliance (e.g., NIH, SBIR/STTR)

• Bachelor’s degree in Finance, Accounting, or related field (MBA, CPA, or CFA strongly preferred)
• 10–15+ years of senior financial leadership experience in biotechnology or life sciences
• Demonstrated experience taking a biotech company through IPO or IPO readiness
• Strong working knowledge of SEC reporting, GAAP, internal controls, and audit processes
• Experience with venture-backed, clinical-stage, or R&D-intensive organizations
• Familiarity with PIPEs, crossover investors, and public-market capital strategy group?
• Executive presence with the ability to engage effectively at the Board and investor level
• Comfortable operating in lean, entrepreneurial environments

• High-impact executive position with direct influence on capital-markets strategy
• Flexible, part-time / fractional engagement suitable for seasoned CFOs
• Opportunity to help position a differentiated biotech platform for public-market execution
• Mission-driven company with strong ESG alignment and meaningful therapeutic ambition

Qualified candidates (or trusted referrals) should send a resume and brief cover note referencing Job Code: APH-2601-01 to: 📧 🌐

No phone calls, please. Aphios Corporation is an equal opportunity employer.