Sr. Scientist, Analytical R&D

Overview

The Materials and Biophysical Characterization group in Analytical Research and Development is seeking a highly self-motivated and innovative scientist with deep knowledge and strong problem-solving skills in biophysical characterization. The Biophysical Characterization team is responsible for building the mechanistic understanding of the interplay between formulation composition, process and stability of drug substance and drug product to ensure process robustness and product quality.

• As a Senior Scientist, you will be supporting projects in the pipeline by developing and implementing biophysical and particle characterization assays collaborating with process, formulation and device as part of the CMC development team.
• You are expected to use your scientific expertise to find creative solutions to challenging problems which require deep analytical insight and critical thinking.
• Additional responsibilities include authoring technical reports and regulatory documents, presenting technical data, and project management.
• You will conduct independent research, publish research findings, present at scientific conferences, and engage with various external scientific societies/organizations.
• This is an excellent growth and learning opportunity to work in an exciting, collaborative environment with a wide array of scientists from different divisions, and make significant contributions towards our life-saving medicines.

• Ph.D. in Biophysics, Biochemistry, Chemistry, Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline with 0-4 years’ experience.
• MSc in Biophysics, Biochemistry, Chemistry, Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences or related discipline with 4-8 years’ experience.

• Fundamental understanding of protein science, protein stability, and protein-protein interactions
• Hands-on experience with biophysical and particle characterization techniques for biotherapeutics characterization, excellent analytical skills and the ability to analyze and interpret complex data sets
• Self-motivated with an outstanding scientific track-record; track-record of independent problem-solving applying deep technical and subject matter expertise
• Excellent interpersonal and communication skills, actively engages in two-way communication to build trusting relationships
• Excellent organizational skills to multi-task and manage multiple projects
• Ability to drive operational excellence by clarifying and translating priorities into actionable steps, and ensure expectations are met aligned with agreed standards and methodologies

• Experience with molecular modeling
• Experience with cryo
  
  EM, BioNMR and/or Mass Spectrometry
• Experience with biological formulation development and analytical method development
• Experience with various modalities including peptides, mAbs, ADC, fusion protein

• Accountability
• Adaptability
• Analytical Method Development
• Assay Development
• Bioanalytical Analysis
• Biochemical Assays
• Biomedical Engineering
• Biophysics
• Protein Chemistry
• Project Management
• Mass Spectrometry (MS)
• Nuclear Magnetic Resonance (NMR) Analysis

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit the EEOC Know Your Rights and GINA Supplement pages.

U.S. Hybrid Work Model:
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid model with three on-site days per week and a remote day on Friday, subject to business needs. Certain roles are exempt from this model.

The salary range for this role is $ - $. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive benefits package including medical, dental, vision, retirement (401(k)), paid holidays, vacation, and sick days. More information is available on the company careers site. Applications can be submitted through the company careers site. The posting end date is 02/02/2026.