Associate Principal Scientist, Materials and Biophysical Characterization AR&D

Job Description

The Materials and Biophysical Characterization group is responsible for physical and biophysical characterization of our Company's development pipeline, inclusive of small molecules, biologics, and vaccines. The team is seeking a highly self-motivated and technically focused scientist with experience in biotherapeutics and materials characterization. As an Associate Principal Scientist, you will be responsible for physical characterization of biotherapeutics with focus on protein higher order structure and particles.

You will be working in a collaborative team environment to support our Company's pipeline from discovery through development to commercial launch. You will be leveraging your technical expertise in characterization, partnering with other development scientists to deeply understand our products and processes, participating on cross-functional technical teams and contributing to interdepartmental initiatives. Additional expectations include building a strong network internally and across the external academic and regulatory community.

Furthermore, the selected candidate will be expected to contribute to a culture of scientific excellence, develop a compliance mindset, and collaborate with partners and stakeholders across our company's network. The selected individual will have the opportunity to work with a wide array of scientists from our different divisions and make an impact on our Company's pipeline and our patients’ lives.

• Masters in Biophysics, Biochemistry, Chemistry, Chemical Engineering, Material Sciences, Biomedical Engineering, Pharmaceutical Sciences or related discipline with a minimum of 8 years relevant industrial experience.
• Ph.D. in Biophysics, Biochemistry, Chemistry, Chemical Engineering, Material Sciences, Biomedical Engineering, Pharmaceutical Sciences or related discipline with a minimum of 4 years of relevant experience.

• Strong background in biophysical/biochemistry/physical chemistry/material sciences
• Self-motivated with an outstanding scientific track‑record.
• Excellent interpersonal and communication skills, both verbal and written.
• Track‑record of independent problem‑solving and application of advanced innovative scientific approaches.
• Desire and willingness to learn, contribute and mentor junior scientists in the group.
• Excellent organizational skills to multi‑task and manage multiple projects.

• Experience with biophysical and biochemical techniques for biotherapeutics characterization.
• In‑depth understanding of protein science, protein stability, and protein‑protein interactions
• Rheological characterization of complex fluids or suspensions
• Experience with solid‑state and solution characterization of small and large molecules
• Experience with formulation development and analytical method development.
• Experience with various modalities including mAbs, ADC, cytokine, fusion proteins, gene therapy, engineered cellular therapies

Effective September 5, 2023, employees in office‑based positions in the U.S. will be working a hybrid work consisting of three total days on‑site per week, Monday‑Thursday, although the specific days may vary by site or organization, with Friday designated as a remote‑working day, unless business critical tasks require an on‑site presence. This hybrid work model does not apply to, and daily in‑person attendance is required for, field‑based positions;

facility‑based, manufacturing‑based, or research‑based positions where the work to be performed is located at a Company site; positions covered by a collective‑bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this hybrid work model guidance also does not apply to roles that have been designated as “remote”.

$ - $ (Based on education, qualifications, experience, and location)

We offer a comprehensive package of benefits. Included are medical, dental, vision healthcare and other insurance benefits (for employee and family),…