Executive Director, Development Business Operations
Listed on 2026-02-03
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Management
Data Science Manager, Business Management, Operations Manager -
Business
Business Management, Operations Manager
Executive Director, Development Business Operations
About Us
Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve. Led by Tassos Giannakakos, Jay Edelberg, M.D. and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading Myo Kardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.
We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.
Role Summary
The Executive Director, Development Business Operations establishes and leads development business operations across the clinical portfolio, including budgets and forecasting, metrics and analytics, resource planning, clinical procurement, and site contracts and budgets. This role ensures financial discipline, operational transparency, and data-driven decision-making across development.
Key Responsibilities
- Lead development budgeting, forecasting, and long-range planning across all clinical programs
- Establish portfolio-level metrics, dashboards, and analytics to support operational and financial oversight
- Oversee clinical procurement processes, including CRO and vendor contracting, in partnership with Legal and Procurement
- Lead site contracts, budgets, and payment processes
- Partner with Finance to align development spend with corporate financial planning
- Support resource planning and capacity modeling across development
- Provide operational insights for EC and Board-level discussions
- Build scalable systems and processes to support portfolio growth
- Ability to assess and transform capabilities through AI and Automation solutions or strategies
- Up to 20‑30% domestic and international travel as required
Qualifications
- Bachelor’s degree in business, finance, life sciences, or related field
- 12+ years of experience in development operations, finance, or business operations or advanced degree (PhD, MBA, Masters) and 10+ years of experience
- Strong experience managing clinical budgets, vendors, and site financials
- Highly analytical with strong executive communication skills
Equal Employment Opportunity
As set forth in Kardigan’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
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