Vice President, Head of Global Translational Medicine & Research

About Genmab

At Genmab, we are dedicated to building extraordinary futures together by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals' unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

As the Vice President, Head of Translational Medicine & Research, you will lead a global organization of 60+ scientists based in the US and the Netherlands. The team spans a broad spectrum of capabilities and plays a pivotal role in shaping translational strategies from discovery through late-stage clinical development.

Global Head of Translational Medicine & Research (TM&R) will report to the Head of Translational & Quantitative Sciences. You will represent TM&R on the Translational & Quantitative Sciences Leadership Team and be responsible for:

• Providing scientific and strategic direction for the delivery of comprehensive pre-clinical and clinical translational data packages and derived insights, ensuring alignment with organizational goals and regulatory standards
• Advancing biomarker strategies and applying insights to clinical development
• Driving innovation, scientific excellence, and team development
• Acting as an ambassador of Genmab science in both internal and external forums

This is an exciting opportunity to lead a passionate, high profile, high-impact translational team, and work in a highly dynamic and collaborative setting.

We have a hybrid model that requires being onsite 60% of the time in Princeton, NJ or Utrecht, NL.

Strategic and scientific leadership

• Lead global TS TM&R efforts supporting translational strategies, planning, data generation, and insight delivery across all stages of development
• Oversee the development and implementation of biological mechanisms into actionable hypotheses to guide translational strategies that inform trial design, dose optimization, patient selection/stratification, combinations, efficacy monitoring and drive data-driven decision-making
• Conduct recurrent reviews of translational strategies across the portfolio to refine strategic and tactical approaches based on emerging data, medical need, and changes in the treatment landscape
• Support data contextualization for regulatory submissions, publications, and scientific communications
• Review and approve integration of translational content into regulatory applications including INDs, BLAs, Clinical Study Protocols and Reports, and other regulatory documents (Technical Reports, Regulatory submissions and responses, etc.) Represent TM&R across internal governance bodies and external collaborations
• Champion the application of novel technologies to inform decision-making and enable compound differentiation
• Partner with cross-functional teams to implement AI/ML models for translational insight generation to optimize and accelerate asset development
• Contribute to building foundational knowledge across formats, targets, and safety profiles

External engagement

• Actively engage with key opinion leaders, technology companies, foundations to advance translational initiatives
• Oversee scientific writing, ensuring high-quality contributions to patents, regulatory documentation, publications, and external presentations across the portfolio
• Present Genmab's translational science at global conferences, expert panels, and in collaboration with academic institutions
• Participate in patient advocacy groups and support initiatives to advance patient engagement

Team development

• Strategically plan workforce capabilities and enable a high-performing global team
• Promote scientific and leadership development through…