Senior System Engineer

Talent Burst, an Inc 5000 company provided pay range

This range is provided by Talent Burst, an Inc 5000 company. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

$60.00/hr - $80.00/hr

Direct message the job poster from Talent Burst, an Inc 5000 company

May do an occasional travel to the Santa Clara jobsite for training etc.

We are seeking a highly motivated Senior System Engineer to join our End-to-End Solution Integration Chapter supporting Next-Generation Diagnostic Solutions.

In this hands-on role, you will drive feasibility, development, and integration of complex multi-disciplinary systems spanning sample preparation, library preparation, molecular detection technologies (e.g., digital PCR, sequencing by synthesis, microarray), and bioinformatics/data processing pipelines.

You will collaborate with assay, software, hardware, and bioinformatics teams to define, integrate, and optimize system-level performance, ensuring technical robustness and operational scalability across diverse technologies.

This role is ideal for a systems-minded engineer with direct industry experience in sequencing workflows, strong analytical and statistical skills, and the ability to influence cross-functional projects without formal people management responsibilities.

Systems Development, Integration & Analysis

Drive system-level development activities across wet lab workflows, instruments, and data pipelines for next generation diagnostic solutions.

Perform hands-on system integration and troubleshooting of workflows including sample extraction, library preparation, molecular detections, and data transfer.

Partner with assay, software and bioinformatics teams to ensure seamless integration of sequencing output with downstream analysis pipelines.

Apply statistical analysis and Design of Experiments (DoE) methodologies (e.g., JMP, ANOVA, regression) to characterize, optimize, and set subsystem specifications.

Plan, design and execute verification and validation (V&V) test cases to ensure comprehensive coverage of requirements.

Analyze test results for accuracy, validity, and relevance to user needs.

Support post-launch troubleshooting and field investigations through failure mode and root cause analyses.

Represent Systems Engineering in cross-functional project teams on key topics such as requirements management, defect management, system integration, etc.

Collaborate closely with assay scientists, software developers, hardware engineers, and bioinformaticians to align on end-to-end workflows.

Contribute to system documentation, including requirements, specifications, integration plans, and verification results.

Identify and lead opportunities for workflow simplification, automation, and continuous improvement.

We are hiring a Senior System Engineer with major in Systems Engineering, Bioengineering, Biomedical Engineering. The final compensation will be determined by the candidate's experience and qualifications.

PhD degree with related field with 5+ years of relevant industry experience is highly valued.

Master's degree with 10+ years of relevant industry experience;

Or Bachelor's degree with 10+ years of relevant industry experience.

hands-on industrial experience with sequencing related workflows, including nucleic acid extraction, library preparation, and sequencing.

Proven lab troubleshooting experience in sequencing workflows and PCR-based workflows.

Exposure to bioinformatics/data processing pipelines for sequencing output (variant calling, data QC) is highly desirable.

Experience with statistical tools and DoE methodologies (JMP, regression, ANOVA) is required.

Familiarity with system-level product development in life sciences instrumentation is a plus.

Experience across multiple product life-cycle stages is a plus.

терминальнийExperiences in digital PCR platforms is desirable.

Experience with developing In-vitro Diagnostic products is desirable.

Experience in implementing workflow on semiconductor based sensing devices or microfluidic devices is…