Distinguished Scientist, Multiomics Discovery – Therapeutics Discovery

Overview

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Learn more at

Job Function
:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function
:
Biological Research

Job Category
:
Scientific/Technology

All Job Posting Locations
:
Cambridge, Massachusetts, United States of America;
Spring House, Pennsylvania, United States of America

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at

We are searching for the best talent for a Distinguished Scientist, Multiomics Discovery to be located in Spring House, PA or Cambridge, MA.

Purpose
:
Discovery Technologies & Molecular Pharmacology (DTMP) has established over 20 high‑throughput, high‑dimensional Multiomics platforms that have generated more than 2.5B data points over the last five years. We are recruiting a Director‑level Distinguished Scientist — an individual contributor and matrix leader — to serve as subject matter expert for Multiomics across internal teams and external collaborators. This role will interpret high‑dimensional platform outputs, support data/metadata quality and provenance, prioritize cross‑platform experiments, and translate integrated evidence into actionable decisions for target /validation, modality selection, biomarker development, early safety signals, and patient stratification from target concept to NME.

Structured without direct reports to preserve deep technical focus, the Distinguished Scientist will exert matrix influence across Therapeutic Area partners, translational teams, Therapeutic Discovery modality groups, IT, DSDH, ISD, and internal discovery teams to accelerate time‑to‑insight and improve ROI on platform investments. Critically, this individual will lead and shape external scientific partnerships, engage academic collaborators, consortia, CROs, and industry partners to drive Multiomics innovation, negotiate technical strategies and data sharing, and expand Multiomics capabilities while delivering measurable portfolio impact.

• Innovative Multiomics Interrogation and Applications:
  Developing and implementing advanced platforms that integrate in vitro, in vivo, human, and molecular data to generate robust hypotheses and simulate biological processes.
• Platform Integration & Tool Development:
  Leveraging innovative foundation models to enhance and streamline assay development, translational biology, and safety predictions. Lead the creation of tools that integrate biological insights across molecular, cellular, and organismal scales.
• Data-Driven Discovery:
  Partnering with internal wet and dry lab collaborators within Multiomics discovery as well as external TA, DSDH, IT, and ISD partners, oversee efforts to generate and integrate diverse data streams to uncover critical insights that drive therapeutic breakthroughs.
• Strategic Vision & Leadership:
  Defining and implementing a transformative roadmap in vitro / in vivo correlations to enable human translation through integrated Multiomics. Matrix leadership across scientific domains and functions.
• Therapeutic Innovation &
  
  Collaboration:
  
  Championing novel approaches to therapeutic hypothesis generation and modality selection, partner with data science, translational, and discovery teams to accelerate the journey from discovery through development.

A PhD in Computational Biology, Biology, Bioinformatics or a related field is required.

• 10+ years of experience in computational technology development and drug discovery, with demonstrated expertise in applying computational biology to drive program progression is required.
• Exceptional communication skills and experience…