Principal Security Engineer
Listed on 2026-01-12
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IT/Tech
Cybersecurity, Systems Engineer
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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.
We’re looking for people who are determined to make life better for people around the world.
As a Security Engineer, you will serve as a technical lead for security consulting engagements and threat modeling initiatives. You will develop complex threat models, security architectures, and reference patterns while providing guidance on secure design principles. This role involves significant collaboration with various teams to integrate security practices into the development lifecycle and conducting security architecture briefings.
How You’ll Succeed- Technical expertise:
You will demonstrate strong domain knowledge in security engineering and threat modeling methodologies. - Strategic thinking:
Success requires the ability to develop reference architectures and integrate complex systems like Zero Trust architectures. - Consultative approach:
You will provide expert security consulting services and guidance to various teams and stakeholders. - Leadership:
Strong ability to lead technical initiatives and mentor other security professionals. - Innovation:
You will actively promote new security approaches and best practices across teams. - Communication:
Excellence in conveying complex security concepts to diverse audiences.
- Develop and conduct complex threat modeling exercises
- Create and maintain security architectures and design patterns
- Provide security consulting services across the organization
- Lead the integration of Zero Trust architectures and other complex systems
- Conduct security architecture briefings and workshops
- Develop and document security best practices
- Mentor junior security engineers
- Drive the adoption of security standards and patterns
- Perform security architecture reviews and assessments
- Contribute to reference architecture development
- Deep understanding of threat modeling methodologies and frameworks
- Experience with security architecture design and implementation
- Strong background in security consulting and risk assessment
- Knowledge of Zero Trust principles and architecture
- Expertise in security frameworks (MITRE ATT&CK, STRIDE)
- Strong analytical and problem-solving abilities
- Excellence in technical documentation and communication
- Experience in mentoring and knowledge sharing
Project management and strategic planning skills - Commitment to continuous learning and professional development
- Bachelor’s Degree in Computer Science, Information Security, or related field Or High School Diploma/GED with 4+ years of experience in Information Security
- At least 5+ years of cybersecurity or related experience
- Extensive experience in threat modeling and risk assessment
- Expertise in security architecture design
- Strong understanding of Zero Trust principles
- Proficiency in security consulting
- Excellence in technical documentation
- Advanced knowledge of security frameworks and methodologies
- Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status)
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form () for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
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