Life Science Research Professional

Overview

School of Medicine, Stanford, California, United States. Department of Genetics at Stanford University seeks a 1 year fixed term Life Science Research Professional (LSRP) I to join William Greenleaf’s lab, focusing on new, high-throughput technology for biochemistry and chromatin biology. The LSRP will be an integral member of a diverse and interdisciplinary research team determined to transform the study of biomolecular interactions and cellular epigenomes.

Current priorities include exhaustive profiling and biophysical modeling of sequence landscapes for DNA binding proteins, and characterization of newly discovered and engineered CRISPR enzymes. Other projects in the lab include building a genome-level human cell atlas of gene expression and DNA accessibility and improving single-cell genomic technologies. More broadly, the Greenleaf lab joins the rest of the Genetics department in crafting sequencing- and big data-driven answers to longstanding questions regarding the physical basis of gene regulation and cellular differentiation.

• Specific tasks include being trained for and performing a technique newly developed in the Greenleaf lab – massively parallel filter binding – and maintaining and expanding the constituent equipment as needed. The LSRP will also be expected to contribute their own ideas and techniques to the lab and attend lab meetings and journal clubs.
• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
• Independently conduct experiments; maintain detailed records of experiments and outcomes.
• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with a senior researcher.
• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
• Assist with orientation and training of new staff or students on lab procedures or techniques.
• Other duties may also be assigned.

• Bachelor's degree in Bioengineering, Genetics, Biochemistry, or Molecular Biology.
• Experience with general molecular biology techniques, such as PAGE, PCR, qPCR, etc.
• Experience performing and analyzing experiments independently for a scientific publication
• Experience with tissue culture
• Familiarity with CRISPR/Cas9
• Experience with high-throughput sequencing methods

• Bachelor's degree in related scientific field.

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
• Ability to maintain detailed records of experiments and outcomes.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Ability to work under deadlines with general guidance.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

• None.

Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.

Must have correctible vision to perform duties of the job. Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours. Ability to lift heavy objects weighing up to 50 pounds. Ability…