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Software Product Manager

Job in Palo Alto, Santa Clara County, California, 94306, USA
Listing for: Guardant Health
Full Time position
Listed on 2025-12-02
Job specializations:
  • IT/Tech
    Data Science Manager, AI Engineer, Data Security, Data Analyst
Job Description & How to Apply Below
** Company Description
** Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.

For more information, visitand follow the company on,and.

The Software Product Manager is a key role within our Product Development & Product Software team, which is responsible for product strategy and technology implementation across our oncology diagnostic product portfolio. The department comprises both assay and software products, including integration of laboratory systems through digital platforms and bioinformatics infrastructure.

As Software Product Manager, you will lead the customer experience and laboratory informatics product portfolio strategy and implementation plan for a franchise vertical, integrating the competitive and technology landscapes, scientific requirements, and business priorities into concrete initiatives with defined outcomes. Together with engineering and laboratory operations teams, you will organize and plan implementation programs for each major initiative, mapping system architecture, integration requirements, and delivery timelines.

You will collaborate closely with cross-functional teams to advise on and execute those programs and ensure on-time, on-budget, and on-spec  this role, you will work at the intersection of software development and engineering, bioinformatics, clinical operations, and user experience as the accountable leader for software initiatives from inception...through execution...to outcome.
**** Core Competencies
***** Analytical and Data Driven:
Measure product performance and adoption with KPIs, metrics, and data, incorporating user feedback to continuously iterate and improve.
* Cross-functional Collaboration and Communication:
Coordinate alignment across engineering, clinical operations, regulatory, and business stakeholders. Collaborate closely with stakeholders to define business and user requirements, prioritize competing demands, manage trade-offs, and clearly communicate business value and rationale.
* Technical Expertise:
Deep understanding of software development, APIs, cloud infrastructure, data pipelines and integration, and analytics systems. Partner closely with engineering, design, data, and bioinformatics to build innovative, scalable, and technically sound software products that align with company objectives and goals.
* Execution:
Guide software product development cycles end-to-end, ensuring timely delivery and quality through SDLC practices.
* Strategic Thinking:
Define and lead the software product requirements (e.g., Product Requirements Document) within your franchise. Identify emerging software technologies and development trends to inform long-term product franchise vision. Assist technical teams with identifying opportunities to optimize development effort based on patterns and trends.
**** Essential Qualifications
***** Typically requires a university degree and generally 8 years of related experience; 6 years and a Master’s degree; 3 years and a PhD; or Pharm

D/MD. Degree in Computer Science, Engineering, or related technical field; advanced degree is a plus.
* Experience in software product management, software engineering, or related technical leadership roles, with at least 2 years prior, in a product management role.
* Understanding of clinical laboratory workflows
* Experience and proven track record of building enterprise software solutions end-to-end, preferably with LIS and/or LIMS (Lab Vantage or similar) and bioinformatics software.
* Deep understanding of software architecture, databases, APIs, cloud platforms, and system design—able to collaborate deeply with engineers and architects.
* Exceptional organizational,…
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