Associate Medical Director

Career Opportunities with Summit Therapeutics Sub, Inc.

Careers At Summit Therapeutics Sub, Inc.

Current job opportunities are posted here as they become available.

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, andour commitment to people.

Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi:
Phase 3 clinical study which was intended to evaluateivonescimabcombined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locallyadvancedor metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi-3:
Phase 3 clinical study which is intended to evaluateivonescimabcombined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

HARMONi-7:
Phase 3 clinical study which is intended to evaluateivonescimabmonotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

HARMONi-GI3:
Phase 3 clinical study intended to evaluateivonescimabin combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimabis an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and hasadditionaloffices in California, New Jersey, the UK, and Ireland.

The Associate Medical Director will help oversee global clinical trials and BLA (Biologic Licensing Application) filings. The incumbent will be primarily responsible for developing and executing integrated clinical trial programs including protocol design and medical oversight of new or ongoing studies. They will be responsible for obtaining scientific advisory input, work with biostatisticians for design and analyses, support regulatory interactions for product advancement, and work closely with clinical operations to provide advice and decision making regarding medical input to achieve operational excellence.

The candidate will serve as a key medical expert for multiple cross functional teams. This position will provide medical insight across a myriad of functions from discovery to manufacturing. Additionally, the Associate Medical Director will play a pivotal role in leading investigator engagements including travel to support face-to-face interaction and protocol training. The Associate Medical Director will serve as a leader on one or multiple, potentially pivotal, programs.

• The role will require knowledge in the treatment and management of oncology disease such that knowledge can be applied to the strategy and clinical development of Summit medicines to benefit patients.
• Work cross functionally with Medical Affairs, Regulatory, Commercial and other functions to develop the overall product strategy in multiple indications
• Work cross functionally with Clinical Operations, Biometrics, Pharmacovigilance, and other functions to successfully complete clinical development programs leading to BLA approvals
• Lead teams to execute on clinical development goals (clinical trial execution, clinical development strategy, medical affairs planning)
• Contribute to the communication strategy of Summit products via publications, manuscripts, abstracts, posters and scientific presentations
• Making vital contributions on pivotal programs in clinical development program
• Directing human clinical trials, phases 1-3, for lead candidate in development, helping to…