AI Sustaining Engineer Principal - AI Center of Excellence - Remote

At Prime Therapeutics (Prime), we are a different kind of PBM, with a purpose beyond profits and a unique ability to connect care for those we serve. Looking for a purpose‑driven career? Come build the future of pharmacy with us.

AI Sustaining Engineer Principal - AI Center of Excellence - Remote

The Principal Artificial Intelligence (AI) Engineer drives the modernization of Prime’s AI capabilities by designing, optimizing, and advancing innovative solutions that unlock business insights, improve operational efficiency, and reduce costs. This role serves as a strategic thought leader—shaping vision, influencing senior leadership, and championing forward‑thinking AI practices that align technology investments with enterprise goals. Through deep expertise and innovation, the Principal AI Engineer ensures Prime remains competitive and future‑ready.

• Serve as a subject matter expert in AI and Machine Learning to support and advance Prime’s strategic initiatives.
• Lead cross‑functional teams to identify, evaluate, and prioritize AI solutions that drive measurable business impact.
• Influence senior leadership on AI strategy, best practices, and opportunities for efficiency and data‑driven decision making.
• Promote organizational awareness and understanding of AI capabilities, processes, and value.
• Oversee the development of AI systems and provide direction to team members to ensure alignment across subsystems and development efforts.
• Perform additional duties as assigned.

• Bachelor’s degree in computer science or related area of study, or equivalent combination of education and/or relevant work experience;
  High School Diploma or GED equivalent required.
• 7 years of extensive technical experience in variety of application development, software development, machine learning or analytics.
• Must be eligible to work in the United States without need for work visa or residency sponsorship.

• Exceptional communication skills, including written, technical, and verbal communication, with the ability to explain complex concepts to diverse audiences.
• Strong analytical and problem-solving abilities, with demonstrated experience in business analysis and solution design.
• Proven adaptability and success working in fast-paced, rapidly evolving environments.
• Proficiency in SQL, including designing and building denormalized data structures within SQL Server environments.
• Leadership capabilities, including guiding work direction, mentoring team members, providing constructive feedback, and influencing outcomes across teams.
• Understanding of product and process engineering within healthcare environments, including workflow optimization and operational impact.
• Awareness of security implications across domains, ensuring solutions align with compliance, privacy, and organizational security requirements.

• Master’s degree in engineering or related field.
• Experience working in environment with regulatory compliance requirements (HIPAA, PCI, etc.).
• Previous experience working in a rapid iterative prototyping environment.
• Previous experience in PBM / health care industry.

Potential pay for this position ranges from $ - $ based on experience and skills.

To review our Benefits, Incentives and Additional Compensation, visit our Benefits Page () and click on the “Benefits at a glance” button for more detail.

Prime Therapeutics LLC is proud to be an equal opportunity and affirmative action employer. We encourage diverse candidates to apply, and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sex (including pregnancy), national origin, disability, age, veteran status, or any other legally protected class under federal, state, or local law. We welcome people of different backgrounds, experiences, abilities, and perspectives including qualified applicants with arrest and conviction records and any qualified applicants requiring reasonable accommodations in accordance with the law.

Prime Therapeutics LLC is a Tobacco-Free Workplace employer.

If you are an applicant with a disability and need a reasonable accommodation for any part of the employment process, please contact Human Resources at or email