Post Doctoral Fellow, Medicinal Chemistry

Overview

Headquartered in Carlsbad, California, Ionis has offices in Boston, Massachusetts, and Dublin, Ireland. Ionis has been at work for more than three decades discovering medical breakthroughs in RNA-targeted medicines. Our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs, with multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs.

We are positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that success is a result of exceptional talents and dedication of our employees. We invest in onsite, hybrid and remote work environments to build lasting relationships and support our culture and employees.

We are building on our rich history and believe our greatest achievements are ahead. If you are passionate about making a meaningful impact on patients in need, we invite you to apply and join us.

Postdoctoral Fellow – Nucleosides/Oligonucleotides Medicinal Chemistry

We are looking for a motivated and creative scientist to join our Medicinal Chemistry team, focused on novel nucleosides and oligonucleotides for ASO- and siRNA-based therapeutics. The successful candidate will be highly skilled in synthetic organic chemistry and work at the interface of synthetic chemistry and oligonucleotide drug technology and discovery. The selected candidate will work alongside a talented team of synthetic and computational chemists, biochemists, biologists and pharmacologists to help discover the next generation of nucleosides and oligonucleotides for ASOs and siRNA programs.

• Design, execute and troubleshoot synthetic organic chemistry routes relevant to the postdoctoral project
• Analyze and interpret results, and present at internal meetings and scientific conferences
• Writing original research manuscripts for scientific publication(s)

• Possess a Ph.D. in synthetic organic chemistry/nucleic acid chemistry, or related fields with 0-3 years of postgraduate training
• Demonstrated expertise to plan and execute multi-step synthesis of complex molecules
• Experienced in modern chromatographic and analytical techniques like TLC, column chromatography, HPLC and NMR to purify and characterize organic compounds
• A track record of scientific excellence and productivity as evidenced by high quality publications
• Strong interpersonal and communication skills
• Ability to manage multiple assignments effectively in a quickly evolving environment
• Ability to be productive and successful in an intense work environment
• Have a passion and enthusiasm for working at the cutting-edge of science
• Required to be full-time onsite at Carlsbad, CA

Ionis offers an excellent benefits package. Ionis Benefits details are available on our careers page.

Pay range: $65,000 to $87,000

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.