Senior Research Associate/Senior Scientist, Core Research
Carlsbad, San Diego County, California, 92002, USA
Listed on 2026-01-27
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Research/Development
Research Scientist, Clinical Research
Overview
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.
At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team.
We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us.
Experience and contribute to our unique culture while you develop and expand your career!
Summary
We are seeking a highly qualified and motivated individual to perform basic research to increase our understanding of how ASOs target RNA to modulate the expression of genes. The position offers the opportunity to do groundbreaking science and make discoveries that will create the next generation of ASO medicines. The selected candidate will become an integral part of an interdisciplinary and energetic team of scientists in the Ionis Core Research group.
Requirements
- Ph.D. degree in biochemistry, molecular biology or cell biology with at least 2 years of post-grad laboratory experience; or a M.S. with at least 3 years post-grad laboratory experience
- Extensive experience in the RNA field with a focus on RNA metabolism, transcription, gene regulation, or epigenetics
- Extensive experience with basic laboratory techniques such as cell culture, transfection, qPCR, cloning, and western blotting
- Experience with advanced laboratory techniques frequently used in RNA research such as ChIP-seq, RNA-seq, FISH, SHAPE, and CRISPR editing
- Proven track record of innovative research, including publications in top tier scientific journals
- Self-starter who is a critical thinker, has a strong work ethic and is not afraid to take risks
- Outstanding organizational, communication and team skills
- Ability to be productive and successful in an intense work environment
Please visit our website, for more information about Ionis and to apply for this position; reference requisition # IONIS
003839. Ionis offers an excellent benefits package.
Ionis Benefits
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Full Benefits Link: ,Benefits,-Employees%20are%20rewarded
The pay scale for this position is $95,929 to $155,277. The pay scale for the Senior Research Associate position is $95,929 to $115,825. The pay scale for the Senior Scientist position is $123,081 to $155,277. NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
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