Senior Site Contracts Manager; Sponsor Dedicated​/Remote

Senior Site Contracts Manager (Sponsor Dedicated / Remote – US Based)

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.

• We are committed to our Total Self culture - where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.

• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives - we're able to create a place where everyone feels like they belong.

Are you a contracts expert who thrives on navigating complexity, building strong site partnerships, and driving timelines forward? Syneos Health is seeking a Senior Site Contracts Manager to support a sponsor dedicated program focused on high impact Pharma & Vaccine studies. If you're energized by problem solving, negotiation, and leading projects across multiple therapeutic areas—especially oncology,we'd love to meet you.

As a Senior Site Contracts Manager
, you'll serve as a strategic expert responsible for developing, negotiating, and managing US site budgets and clinical trial agreements. You'll collaborate closely with internal teams, external stakeholders, and major academic institutions to craft robust contracts that support operational excellence while minimizing risk.

This role is perfect for a communicator, leader, and negotiator who's ready to hit the ground running and make an immediate impact.

• Build US site budget templates and study specific budget language for Pharma & Vaccine clinical trials.

• Develop and refine templates to support consistency, compliance, and strategic study needs.

• Lead direct negotiations with large academic institutions and other critical stakeholders.

• Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections.

• Conduct due diligence checks—such as FMV assessments and site justification reviews—when initial offers are declined.

• Determine when requests require budget or language escalation and secure appropriate approvals.

• Prioritize and lead multiple contracting projects across several therapeutic areas (oncology experience strongly preferred).

• Proactively elevate risks, timeline impacts, or delays that could affect CTA execution.

• Demonstrate expert proficiency in Excel and clinical trial management systems.

• Communicate effectively in both written and verbal formats, incorporating feedback seamlessly.

• Maintain accurate and timely updates in departmental trackers and databases.

• Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies.

• Build strong working relationships with internal and external partners.

• Support and train additional team members as needed.

• Contribute to process improvement…