Assistant Director, IT Cloud and Identity Engineer

Assistant Director, IT Cloud and Identity Engineer

Job Category
: R&D Support - Ionis

Requisition Number
: IONIS
003874

• Posted :
  January 30, 2026
• Full-Time

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Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA‑targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

ASSISTANT DIRECTOR, IT CLOUD AND IDENTITY ENGINEER

SUMMARY:

This Senior Engineer–level individual contributor leverages deep experience as a senior infrastructure engineer/administrator to provide technical leadership for Ionis’s cloud and identity platforms and drive modern infrastructure operations. The primary responsibility is to lead cloud engineering across Azure and AWS, manage enterprise identity and access with Okta, and support core infrastructure services for the broader environment. This position partners IT security and IT application owners to tackle complex, cross‑functional challenges and deliver secure, scalable, and highly reliable services across the enterprise.

This position will be on‑site in our Carlsbad, CA location and open to flexible/hybrid schedule.

RESPONSIBILITIES:

Cloud Engineering & Operations

• Lead cloud engineering and operations for Azure (primary) and AWS (supporting), including platform administration, reliability, performance, and cost optimization.
• Design, implement, and manage Azure subscriptions across multiple regions, with a strong focus on scalability, availability, and security.
• Establish and maintain operational processes for monitoring, availability, incident response, and continuous service improvement.

Cloud Architecture, Governance & Security

• Provide technical governance and oversight for Azure and AWS, ensuring alignment with enterprise architecture, security, and compliance standards.
• Partner with Information Security to design and implement cloud security controls, including Identity Access Management (IAM), network segmentation, logging, monitoring, and audit readiness.
• Collaborate with Information Security to design and enforce identity and access controls such as RBAC, conditional access, MFA, and privileged access management across cloud and enterprise applications.

Identity Access Management

• Administer and enhance Okta workforce identity, including authentication, authorization, user lifecycle management, and access governance.
• Ensure identity platforms are secure, scalable, and aligned with Zero Trust and enterprise access strategies.

Infrastructure and Platform Collaboration

• Support core infrastructure services— including networking, wireless, email/collaboration, storage, backup/restore, and VMware—in partnership with the broader infrastructure…