Senior Scientist

Sr Scientist

Location: Fully Remote (PST time zone preferred)

Department: Center for Technology Innovation (CfTI), Amgen

Amgen’s Center for Technology Innovation (CfTI) is seeking a highly motivated Computational Biologist to support our clinical portfolio through advanced analytics, biomarker development, and innovative computational approaches. This high‑visibility individual contributor role partners across matrixed teams to design, implement, and apply analytical methods that drive patient selection, biomarker strategy, and clinical decision‑making.

The ideal candidate brings strong expertise in clinical bioinformatics
, statistical modeling
, and biological data analysis
, with hands‑on experience working with clinical datasets. Experience in prostate cancer or solid tumor biology is highly desirable.

• Develop and apply computational, statistical, and machine learning methods to analyze multi‑modal, multi‑dimensional, and large‑scale clinical and translational datasets.
• Translate biological and clinical questions into rigorous analytical frameworks that generate actionable insights.
• Support biomarker discovery and clinical assay development across flow cytometry, IHC, NGS, immunoassays, imaging, and transcriptional profiling platforms.
• Collaborate across highly matrixed teams to drive scientific and technical innovation within CfTI and the broader Amgen research community.
• Contribute to patient‑selection strategies, time‑series and survival analyses, and clinical data integration efforts.
• Ensure analytical rigor and compliance with assay qualification requirements for clinical trial support.

• PhD in Bioinformatics, Mathematics, Statistics, Computer Science, Data Science, or a related field;
• OR M.S. with 3+ years of relevant industry experience.

• Significant experience in bioinformatics, applied mathematics, and/or statistics, including linear mixed‑effects modeling.
• Working knowledge of machine learning and AI technologies; experience applying ML/AI in clinical trial settings is a plus.
• Hands‑on experience with clinical biomarker platforms (flow cytometry, IHC, NGS, immunoassays, imaging, transcriptional profiling).
• Deep understanding of prostate cancer or solid tumor biology.
• Proficiency in R and Python, including tidyverse principles.
• Familiarity with assay development and qualification for clinical trial support.
• Strong communication skills, self‑motivation, and the ability to lead and influence in a matrixed environment.

This is a Contract position based out of Thousand Oaks, CA.

The pay range for this position is $45.00 - $47.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre‑tax and Roth post‑tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long‑term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type:
This is a fully remote position.

Final date to receive applications:
This position is anticipated to close on Jan 16, 2026.

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The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

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