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Principal Analyst, Microsoft 365 Security & Data Protection; Remote

Remote / Online - Candidates ideally in
Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Vertex Pharmaceuticals Incorporated
Remote/Work from Home position
Listed on 2026-01-12
Job specializations:
  • IT/Tech
    Data Analyst, Data Security
Salary/Wage Range or Industry Benchmark: 141200 - 211800 USD Yearly USD 141200.00 211800.00 YEAR
Job Description & How to Apply Below
Position: Principal Analyst, Microsoft 365 Security & Data Protection (Remote role)

Job Description General Summary

This person will be responsible for the day-to-day administration of the Microsoft 365 Purview and Entra , as well as the Veritas Data Insight platform, in a heavily-regulated GxP environment. This person will be responsible for working with business and technical leaders to identify systems containing critical data and labeling them accordingly. S/he will be responsible for creating data protection awareness programs for end-users and using standardized metrics to document compliance.

S/he will participate in incident investigations and assist, when necessary, to resolve complex software and hardware problems. This person will be required to follow strict change control processes and perform other tasks as assigned by management.

Key Duties and Responsibilities
  • Must have expert-level experience with managing and configuring Microsoft Purview and Entra  it relates to Conditional Access policies, Sensitivity Labels, data classification, data sensitivity labels, e-Discovery, management of the Entra  process, and creation of rules and alerts within Microsoft CASB.
  • Ability to use Microsoft Purview to produce operational metrics on a regular basis for management review.
  • Proven experience supporting and deploying functionality provided through the Microsoft Defender Portal and the Microsoft 365 Security & Compliance Center, including Audit, Activity Explorer, and other data protection controls.
  • Support initiatives performed by the Vertex Microsoft 365 team to ensure compliance and operational effectiveness from an Information Security and data protection perspective.
  • Create training materials to expand the adoption of identifying and labeling data using Microsoft 365 Sensitivity Labels.
  • Must have expert-level experience with Veritas Data Insight. Ability to independently create data usage reports (including DQL reports), integrate new sources of Vertex data, create and deploy policies, generate sensitive information tags, create usage metrics for senior leadership, and other tasks related to identifying/tagging data through the Data Insight platform
  • Experience with SailPoint ISC and Data Access Security is a plus.
  • Any other tasks assigned by the Vertex management team.
Knowledge and Skills
  • Must have 3-5 years of experience with Microsoft 365 Purview and the Microsoft 365 Compliance suite.
  • Must have 3-5 years of experience using Veritas Data Insight, especially policy creation, report creation and DQL.
  • Must have experience with data classification policies and proven abilities to identify data and assign policies accordingly.
  • Experience supporting Microsoft CoPilot as it relates to data discovery.
  • Experience supporting SailPoint is a plus.
  • Ability to work well with peers and all levels of management.
  • Must be able to work independently and produce positive results.
  • Pays strict attention to detail.
  • Very strong organizational, task management and prioritization skills.
  • Desire to learn new technologies.
  • Understands the importance of accuracy and responsiveness.
  • 3-5 years working in an Information Security organization.
  • Excellent written skills.
  • Previous experience in an FDA regulated environment is a plus.
Education and Experience
  • Bachelor's degree or equivalent experience
  • Typically requires 6 years of experience or the equivalent combination of education and experience
Pay Range

$141,200 - $211,800

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off…

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