Sr Director Asset Lead-Oncology

Overview

Site Name: USA - Pennsylvania - Upper Providence, USA - Pennsylvania - Philadelphia

Posted Date:
Feb 3 2026

You will lead the Global Value Evidence Generation Team for an oncology/hematology asset. You will design and oversee evidence generation plans that support clinical and access decisions across development and lifecycle. You will work closely with medical affairs, clinical development, market access, commercial, and external partners. We value clear scientific thinking, collaborative leadership, and the ability to translate evidence into practical actions that improve patient care.

This role offers growth, visible impact, and alignment with GSK’s mission of uniting science, technology and talent to get ahead of disease together.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Lead and mentor the Value Evidence team responsible for health economics, outcomes research and real-world evidence for an oncology asset.
• Develop integrated evidence generation strategies that align clinical, regulatory and access needs across the product lifecycle.
• Partner with clinical development and medical teams to shape study design, endpoints and comparators to meet payer and HTA expectations.
• Oversee delivery of value evidence studies, including protocol development, study execution, analysis and transparent reporting.
• Represent the team in cross-functional governance and in external scientific dialogue with payers, HTA bodies and academic partners.
• Manage resource planning and budget for all evidence activities and track impact of evidence on internal decision-making and external access outcomes.

This role is open as either home based or hybrid position based in the United States. For the hybrid position, you will be expected to spend at least two days per week at the GSK Upper Providence PA office and the remainder of the time working remotely. We welcome applicants from a range of backgrounds and are committed to inclusion in our team.

• Advanced degree (Master’s, PhD, Pharm
  
  D) in health outcomes, epidemiology, health economics, epidemiology, biostatistics, clinical research, pharmacy, medicine, or related discipline.
• 5 + years of experience in health outcomes, real-world evidence or related functions within the pharmaceutical or healthcare sector.
• Hands-on experience with observational study design, comparative effectiveness, economic modeling, or advanced analytical methods.
• Experience designing and delivering evidence generation plans to support reimbursement, market access or regulatory submissions.
• A track record of scientific publications or presentations at major congresses.
• Experience leading cross-functional teams and influencing stakeholders across clinical, medical, commercial and access functions.
• Strong project management skills with experience managing multiple studies and external partners.
• Experience in direct line management.

If you have the following characteristics, it would be a plus:

• Excellent written and verbal communication skills with the ability to present complex evidence clearly to diverse audiences.
• Experience leading teams in oncology/hematology or another complex therapy area.
• Deep knowledge of US and Global payer and HTA landscape, and familiarity with evidence requirements of major payers and value assessment organizations.
• Experience building strategic external collaborations with academic groups, data custodians, or large provider systems.

• A collaborative leadership style that develops people and builds trust across functions.
• Strong scientific judgement and practical problem-solving skills.
• A focus on delivering high-quality, timely evidence that supports patient access.
• The ability to balance strategic thinking with operational delivery.

We encourage qualified candidates who are motivated to make a meaningful impact in oncology value evidence to apply. Please submit your CV and a brief cover note describing your relevant experience and why this role matters to you. We look forward to hearing…