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Senior Director, Computational Biology

Remote / Online - Candidates ideally in
Menlo Park, San Mateo County, California, 94029, USA
Listing for: pacb.com
Full Time, Remote/Work from Home position
Listed on 2026-01-15
Job specializations:
  • Healthcare
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 250000 USD Yearly USD 250000.00 YEAR
Job Description & How to Apply Below
Senior Director, Computational Biology page is loaded## Senior Director, Computational Biology locations:
US - California - Menlo Parktime type:
Full time posted on:
Posted Yesterday job requisition :
JR100789

Title:

Senior Director, Computational Biology Pac Bio  (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems.  Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health.  

We are now entering the century of biology and genomics is at the heart of the next revolution.  Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the Pac Bio team.

The Senior Director, Computational Biology is responsible for leading development of streamlined informatics solutions for HiFi sequencing data that deliver the best clinical and research genomes, transcriptomes, methylomes and metagenomics solutions. This role requires close collaboration with our customers and the scientific community to continually identify and solve the most impactful genomic problems, and plays a critical role in demonstrating what is possible with Pac Bio sequencing for both research and diagnostics.

Responsibilities:
* Lead and mentor a high-performing computational biology organization supporting both research innovation and commercial products.
* Provide strategic guidance to translate customer needs and emerging scientific opportunities into scalable, impactful informatics capabilities.
* Identify and develop opportunities and collaborations which demonstrate new scientific and diagnostic applications for Pac Bio sequencing.
* Provide scientific and technical leadership across the product lifecycle.
* Partner closely with marketing, R&D, engineering and commercial teams to ensure alignment between scientific innovation and product strategy.
* Foster and lead high-impact collaborations with academic, clinical, and industry partners.
* Represent Pac Bio informatics and scientific leadership at national and international conferences, workshops, and commercial events.
* Lead development of informatics and computational solutions suitable for regulated clinical environments.

Required Qualifications:

* Ph.D. in a computational or biological field (e.g., bioinformatics, genetics, genomics, computer science).
* Demonstrated success building scientific software that is broadly used by the genomics community.
* Track record of leading high-impact scientific collaborations and publications as evidenced by a strong publication record and work leading to widely adopted computational tools and methods.
* Demonstrated ability to drive partnerships in both academia and industry.
* Excellent interpersonal, written, and verbal communication skills, with the ability to engage diverse audiences.
* 5+ years of experience in a leadership role at a senior manager level or higher.
* Experience leading multidisciplinary teams and influencing across organizational boundaries.

Preferred Experience:

* Experience in human genomics, including rare disease and/or cancer applications.
* Experience with long-read sequencing analysis and informatics solutions.
* 8+ years of experience in a leadership role at a senior manager level or higher.
* Experience developing and supporting software and computational tools used in regulated or clinical contexts (e.g. CLIA/CAP, FDA/IVDR, GxP).Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

Non-Field Based Employees are required to be onsite Monday-Thursday (Friday work from home).  Depending on the role, some employees may be required to be 100% onsite.

You may be required from time to time to visit and work at Pac Bio locations and for such times as the Company considers necessary for the proper performance of your duties.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.#LI-Onsite
* Salary Range:*$ - $To all Staffing and Recruiting Agencies:
Our Careers Site is only for individuals seeking a job ffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles, applications or resumes, and any such submissions will be considered unsolicited. Pac Bio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias,…
Position Requirements
10+ Years work experience
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