Senior Accountant

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical‑stage company currently focused on post‑bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

Amylyx is seeking a highly motivated professional with accounting experience who can apply accepted accounting principles and procedures to analyze financial information, prepare accurate and timely results, and ensure appropriate accounting control procedures. This position will be a key member of a cross‑functional accounting team. The individual will be responsible for managing critical accounting areas, reconciliations, corporate accruals and ad hoc reporting.

This position will have significant interaction with Amylyx business leaders.

Month‑End Close
:

• Assist with the month‑end close process to ensure timely, accurate, and complete financial reporting.
• Prepare journal entries for cash, investments, prepaid expenses, SG&A accruals, T&E, stock option exercises, and RSU vesting.
• Perform foreign currency translation and revaluation, ensuring accuracy of currency translation adjustments (CTA) and validation of exchange rates.
• Oversee the preparation and distribution of monthly financial reports to internal stakeholders.
• Ensure the preparation and review of intercompany journal entries and balances.
• Ensure internal financial reports are accurate, up to date, and aligned with business needs.
• Ensure compliance with financial reporting controls and maintain accuracy in reports used for internal control purposes.
• Prepare balance sheet reconciliations, ensuring completeness and accuracy.
• Prepare and oversee balance sheet and income statement flux analysis, comparing current periods with prior periods and the prior year.
• Lead the preparation and coordination of foreign statutory financial statements, including managing audits in collaboration with PwC.

Net Suite and Flo Qast Management
:

• Serve as the Net Suite administrator, responsible for maintaining accounts, departments, project codes, and GEO codes, ensuring approval processes are followed.
• Develop, enhance, and maintain Net Suite reports to support internal financial and operational needs.
• Oversee Net Suite cash reconciliation processes and identify opportunities to leverage additional modules.
• Administer Flo Qast by adding new users, assigning reconciliations, and maintaining the month‑end close checklist.
• Lead user access reviews for both Net Suite and Flo Qast to ensure appropriate permissions are maintained.

Tax & Treasury Support
:

• Act as the primary point of support for the Head of Tax and Treasury, providing analysis and data for tax compliance and statutory reporting.
• Assist with the preparation and review of tax‑related disclosures and support the tax filing process.

• Bachelor’s degree in Accounting or Finance
• 4+ years of progressive accounting experience
• Experience with ERP systems, particularly Net Suite
• Advanced proficiency with Microsoft Excel and other Office products

• CPA designation or progress toward obtaining a CPA.
• Experience working in a public company environment or with a Big 4 accounting firm.
• Knowledge of international statutory reporting requirements and foreign currency transactions.

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain…