Engineer II, Manufacturing Systems

Overview

Kriya is a biopharmaceutical company whose mission is to develop life-changing gene therapies for diseases affecting millions of patients around the world.

Department: Ops Tech & Automation

Employment Type: Full Time

Location: Research Triangle Park, NC

Kriya is a biopharmaceutical company whose mission is to develop life-changing gene therapies for diseases affecting millions of patients around the world. We leverage our proprietary computational engine, in-house manufacturing infrastructure, and integrated design platform to engineer technologies and therapeutics with the potential to transform the treatment of a broad universe of diseases of high unmet need, with a focus on metabolic disorders, neurology, and ophthalmology.

We are proud to have been named Triangle Business Journal’s Life Sciences 2024 “Best Private Company to Work For,” recognized by Forbes as one of “America’s Best Startup Employers of 2024,” and honored as one of Bio Space’s “2025 Best Places to Work.”

The Engineer II, Manufacturing Systems is an experienced OT Automation and Manufacturing Engineer responsible for the administration, reliability, and continuous improvement of GMP-critical automation platforms including OSIsoft PI, Siemens Desigo CC, and Delta

V. As a key member of the Operational Technology Automation Manufacturing team, you collaborate with cross functional teams including Manufacturing, Facilities/Engineering, Quality and IT to deliver automation solutions that support production goals and regulatory compliance.

• Configure and maintain OSIsoft PI data historian infrastructure, including interface configuration, data collection optimization, and data archive management.
• Support Siemens Desigo CC building management system operations.
• Monitor system health and performance metrics across all automation platforms, proactively identifying and resolving issues to maximize uptime.
• Execute preventive maintenance activities, software patching, and system updates in accordance with change control procedures.
• Investigate and troubleshoot system alarms, faults, and performance degradation, implementing corrective and preventive actions.
• Support validation activities including IQ/OQ/PQ protocol execution, test script development, and documentation review for automation systems.
• Maintain system documentation including network diagrams, configuration specifications, standard operating procedures, and maintenance records.

• Bachelor's degree in Engineering (Chemical, Electrical, Mechanical, or related discipline) or equivalent technical degree.
• Minimum 3+ years of experience supporting automation systems in pharmaceutical, biotechnology, or regulated manufacturing environments.
• An equivalent combination of education and experience is acceptable
• Familiarity with industrial networking protocols (Ethernet/IP, Modbus, OPC, BACnet) and network infrastructure.
• Knowledge of validation lifecycle and IQ/OQ/PQ protocol execution for automated systems.
• Experience with the life cycle management of at least one of the following systems in a GMP environment:
• Allen Bradley PLCs and FT View
• Emerson Delta
  
  V or Thermo Fisher Tru Bio
• OSIsoft Pi Data Historian System
• Tulip Management of Manufacturing Operations System
• Siemens Desigo Building Management System
• TiPSView Alarm Assessment System
• Proficiency with SQL databases and scripting languages (VBA, Python, or Power Shell) for automation tasks.
• Strong analytical and problem-solving skills with ability to diagnose complex system issues.
• Effective communication skills for technical and non-technical audiences.
• Ability to work independently and as part of cross-functional project teams.

• Primarily desk-based, generally in an office or home office setting
• Occasional tasks performed in a lab or manufacturing clean room environment.
• Must be able to lift desktop computers, small servers, switches, PLCs, and electrical components.
• May be required to work after-hours for OT emergencies or maintenance window activities.

Discover True Collaborative Teamwork. We have an ambitious set of goals, but our confidence – and our inspiration – stems from our people. From California to North Carolina, our teammates bring a spirit of Collaboration, Leadership, and Innovation to their work every day.

We’re always looking for teammates with the drive and energy to help us grow. If you want to be a part of a company with an entrepreneurial culture, a bold vision, and a meaningful purpose, join us.

• Time Off & Work-Life Balance:
  Flexible Time Off ∙ Paid Parental & Medical Leave ∙ Paid Company Holidays
• Health & Wellness:
  Fertility & Family Building Benefits ∙ Medical, Dental, and Vision Insurance ∙ Employee Assistance Program (EAP) ∙ Life Insurance ∙ Short- and Long-Term Disability Coverage
• Financial Security:
  Equity ∙ 401(k) with Company Match ∙ Identity Theft Protection
• And More!