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Engineer Principal – Drug Substance Manufacturing Process Optimization & Tech Transfer; REMOTE

Remote / Online - Candidates ideally in
Holly Springs, Wake County, North Carolina, 27540, USA
Listing for: 3key Consulting, Inc.
Remote/Work from Home position
Listed on 2026-01-12
Job specializations:
  • Engineering
    Manufacturing Engineer, Process Engineer, Quality Engineering
Salary/Wage Range or Industry Benchmark: 55 - 62 USD Hourly USD 55.00 62.00 HOUR
Job Description & How to Apply Below
Position: Engineer Principal – Drug Substance Manufacturing Process Optimization & Tech Transfer (REMOTE)[...]

Job Title

Job Title: Engineer Principal – Drug Substance Manufacturing Process Optimization & Tech Transfer REMOTE (JP14711)

Location

Location: Holly Springs, NC. 27540 (Remote but all job seekers need to commit to two weeks on-site during critical operations and should be local/ willing to travel to Holly Springs, NC. Campus)

Employment Type

Employment Type: Contract

Business Unit

Business Unit: Drug Substance Technology Business Operations

Duration

Duration: 6+ months (with likely extensions and/or conversion to permanent)

Posting Date

Posting Date: 10/28/25

Pay Rate

Pay Rate: $55 - $62/hour W2

Notes

Notes: Only qualified candidates need apply. Remote but all job seekers need to commit to two weeks on-site during critical operations and should be local/ willing to travel to Holly Springs, NC. Campus

Job Description

Remote but all job seekers need to commit to two weeks on-site during critical operations and should be local/ willing to travel to ANC campus.

  • Lead optimization of drug substance processes related to pharmaceutical manufacturing technology transfer; lead sub-teams and provide expertise to support drug substance manufacturing.
  • Provide support for technical troubleshooting in a GMP environment, investigations, and deviation/CAPA strategy.
  • Candidate should be proficient in process monitoring tools, data visualization tools (e.g., Spotfire), and GMP principles.
  • Candidate needs to travel periodically to the manufacturing site for critical activities.
  • Candidate will need to provide second shift process monitoring as needed.
Why is the Position Open?

Supplement additional workload on team.

Top Must Have Skills
  • Proficient in tech transfer
  • Proficient in MFG Support
  • Able to lead sub-teams and provide expertise for technical troubleshooting
Day to Day Responsibilities
  • Lead optimization of drug substance processes related to pharmaceutical manufacturing technology transfer.
  • Lead sub-teams and provide expertise to support drug substance manufacturing.
  • Provide support for technical troubleshooting in a GMP environment, investigations, and deviation/CAPA strategy.
  • Candidate should be proficient in process monitoring tools, data visualization tools (e.g., Spotfire), and GMP principles.
  • Candidate needs to travel periodically to the manufacturing site for critical activities.
  • Candidate will need to provide second shift process monitoring as needed.
Basic Qualifications

Doctorate degree and 3 years of experience OR Masters degree and 5 years of experience OR Bachelors degree and 7 years of experience OR Associates degree and 12 years of experience OR High school diploma / GED and 14 years of experience.

Employee Value Proposition
  • Unique industry opportunity
  • Career growth
  • Networking
Red Flags
  • Lab experience only
  • Unwilling to travel
  • Unwilling to work outside day shift
Interview Process

Video conference interview with hiring manager.

Contact Information

We invite qualified candidates to send your resume to  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website  You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.

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