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Director, Transformation Enterprise Program Office; CRO Operations - NA​/Europe - Remote

Remote / Online - Candidates ideally in
Charlotte, Mecklenburg County, North Carolina, 28245, USA
Listing for: Worldwide Clinical Trials - USA
Remote/Work from Home position
Listed on 2026-03-14
Job specializations:
  • Business
    Business Management, Business Analyst
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below
Position: Director, Transformation Enterprise Program Office (CRO Operations) - NA/Europe - Remote

Who we are

We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way.

Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.

Why Worldwide

We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands‑on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed.

We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day. Join us!

What you will do

Portfolio & Project Delivery:

  • Serve as the single point of contact for all projects within the assigned EPMO portfolio.
  • Proactively engage with and support project teams to monitor progress and ensure the successful delivery of intended value and outcomes.
  • Collaborate with Project Leaders to refine overall project plans, including the establishment of critical milestones and success metrics.
  • Identify, analyze, and help resolve significant blockers to project success, such as lack of stakeholder alignment, fear of change, organizational capability gaps, etc.
  • Prepare and develop clear, concise documentation for executive and board level governance meetings.
  • Lead comprehensive post‑mortems to capture lessons learned and foster a culture of continuous improvement.
  • Integrate the assigned portfolio of projects into the overall EPMO, ensuring alignment with broader enterprise objectives.

Capability Building & Enablement:

  • Coach and mentor Project Leaders on best practices for executing successful, high‑impact projects.
  • Champion and guide the integration of Artificial Intelligence (AI) into project methodologies and solutions.
  • Act as a key enabler of critical resources and support to Project Leaders, including access to expert interviews, targeted research, and analytical support.
  • May supervise direct reports, supporting their performance and development.
What you will bring to the role
  • Exceptional leadership and facilitation skills, with the ability to influence, motivate, and align cross‑functional teams toward a common vision.
  • Advanced strategic thinking, capable of synthesizing complex information and developing actionable plans that drive enterprise value.
  • Outstanding communication abilities, both written and verbal, with a proven aptitude for preparing executive‑level documentation and delivering high‑impact presentations.
  • Superior problem‑solving and critical thinking skills, able to anticipate risks, analyze challenges from multiple perspectives, and implement effective solutions quickly.
  • Strong organizational acumen, including the ability to engage multiple projects simultaneously and prioritize competing demands in a dynamic environment.
  • Deep proficiency in project and portfolio management methodologies / Transformation Office techniques, tools, and best practices.
  • High emotional intelligence and the ability to foster a culture of trust, engagement, and continuous improvement.
  • Change management expertise, with a knack for guiding organizations through ambiguity and transformation.
  • Flexible and adaptable, thriving in fast‑paced, evolving environments, and embracing opportunities to innovate and learn.
  • Technological curiosity and literacy, especially as it relates to emerging trends in Artificial Intelligence and digital transformation.
Your experience
  • Bachelor’s degree in Finance, Economics, Accounting, Business Administration, Engineering, or related field;
    Master’s degree or certifications in Agile, Change Management, or Lean Six…
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