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Research Technician I​/II - Hughes Lab

Job in Oklahoma City, Oklahoma County, Oklahoma, 73116, USA
Listing for: Oklahoma Medical Research Foundation
Full Time position
Listed on 2026-01-12
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research, Medical Technologist & Lab Technician, Medical Science
  • Healthcare
    Clinical Research, Medical Technologist & Lab Technician, Medical Science
Salary/Wage Range or Industry Benchmark: 40000 - 60000 USD Yearly USD 40000.00 60000.00 YEAR
Job Description & How to Apply Below

CAREERS AT OKLAHOMA MEDICAL RESEARCH FOUNDATION

Have big ideas, passion, and a desire to grow? Join us and make a difference.

For multiple consecutive years, Foundation employees have voted OMRF among “Oklahoma’s Top Workplaces.”

Our mission: "...so that more may live longer, healthier lives." Learn more .

Position Overview and Responsibilities

The Hughes Lab within the Aging & Metabolism Research Program is seeking a motivated Research Technician at the I or II level to support studies on the cellular and molecular mechanisms that regulate skeletal muscle size and function, particularly in the context of disease and aging. One interest of the laboratory is understanding the role of post-translational modifications, such as ubiquitination and acetylation, on the regulation of nuclear receptors and in different sexes.

This work involves the use of in vitro and in vivo models with a variety of laboratory techniques to advance our understanding of muscle biology.

Responsibilities include, but are not limited to:
  • Processing tissue samples, including chromatin immunoprecipitation, RNA/DNA isolation and histology.
  • Aiding in implementing rodent experiments tissue collection.
  • Participating in lab meetings and departmental discussions.
Minimum Requirements
  • Bachelor's Degree in one of the biological sciences, physics, chemistry, or related area, or equivalent years of relevant lab experience.
  • Ability to read and comprehend instructions, short correspondence and protocols/procedures.
  • Ability to write routine reports, correspondence and meet deadlines.
  • Ability and willingness to handle laboratory mice and rats, including breeding, maintenance, and procedures as needed.
  • Team player with strong interpersonal and communication skills.
  • Proficiency in Microsoft Office (Word, Excel, PowerPoint).
  • Highly organized and meticulous to ensure accuracy of data collection and recording.
  • Willingness to learn new techniques and initiative to solve problems.
Preferred Qualifications

Candidates with a strong background in Molecular Biology are strongly encouraged to apply. Expertise in any of the following areas is highly valued:

  • Molecular Biology (Genotyping, RNA work, RT-qPCR, DNA-Protein Interaction techniques).
  • Histology (Blocking, Sectioning and Microscope Imaging).
Work Hours

Typically, Monday through Friday from 8:30AM to 5:00PM. Occasional work outside these hours may happen with advanced notice.

OMRF Overview

Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, multiple sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation’s leaders in patents per scientist.

Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a collective commitment to our mission, "so that more may live longer, healthier lives."

Successful candidates will demonstrate commitment to this mission.

OMRF Benefits

We offer competitive salaries and comprehensive benefits to full-time employees including medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, and paid holidays. All employees have access to our onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro.

Learn more about our benefits here.

OMRF is an Equal Opportunity Employer.

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