Scientist, Research Scientist, Data Scientist

* Works as part of a team to support late-stage assay development of biophysical characterization methods such as circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), analytical ultracentrifugation (AUC), size exclusion chromatography with multi-angle light scattering (SEC-MALS), and fourier transform infrared (FTIR) to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context.
* Contributes to analytical method development and qualification to support protein characterization activities.
* Supports comparability and stability studies by higher order structure assessment.
* Operates, maintains, and troubleshoots CD, DSC, AUC, SEC-MALS, and FTIR instruments.
* Works on moderately complex problems where analysis of situations or data requires evaluation of intangible variables requiring regular use of intelligence, logic, ingenuity, and creativity.
* Works in collaboration with junior and senior team members to advance the development of state-of-the-art techniques to characterize substances, assays, and tools.
* Represents the Bio Pivotal Structure group in cross-functional project teams.
* Participates in process comparability studies and coordinates analysis of in-process and product-related impurities as needed.
* Responsible for conducting scientific research for the development of drug candidates or research support of marketed drugs.
* Advises project teams on the planning and execution of laboratory experiments, considering economic, regulatory and safety factors.
* Presents results of work, interprets data, and draws conclusions regarding presented material and nature of work.
* Maintains familiarity of state-of-the art scientific principles and literature and applies such knowledge appropriately to projects and in support of the Company’s interests.
* Represents the company at national/international conferences.
* PhD in Chemistry or a related discipline with limited industry experience,    OR
* MS degree with 4+ years industry experience.
OR
* BS degree with 6+ years' industry experience
* Strong knowledge in mass spectrometry, experimental design, and assay development.
* Familiarity with several of the following is highly desired: circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), analytical ultracentrifugation (AUC), size exclusion chromatography with multi-angle light scattering (SEC-MALS), and fourier transform infrared (FTIR), ultra-performance liquid chromatography, and proteolytic/chemical processing. Knowledge of ICH guidelines and GMP is a plus.
* Expertise in biophysical analysis software and data analysis/visualization tools (Python, R, JMP, and Spotfire).
* Excellent communication skills (both verbal and technical) and interpersonal skills are required. Must be able to participate in highly effective teams.
* Must think critically and creatively and be able to work independently, determine appropriate resources for resolution of problems and have strong organizational and planning skills.
* The candidate will be expected to work in a matrixed environment and be an effective communicator of ideas, assay results and issues.
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