CW Sr Research Associate II

Who We Are

Bio Marin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.

Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.

Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well‑understood biology and provide an opportunity to be first‑to‑market or offer a substantial benefit over existing therapeutic options.

Bio Marin’s Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain Bio Marin’s cutting‑edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.

The selected candidate will work in the Separations and Biophysical Assays team within the Analytical Sciences group to assist in the advancement of Bio Marin's therapeutics for clinical evaluation and potential commercialization. The candidate will be responsible for method development (separations), provide routine testing and characterization support to partner groups to help with early candidate selection, process development, and drug substance and drug product process characterization.

The ideal candidate will have hands‑on experience working with biologics including but not limited to proteins, peptides, protein‑conjugates, enzymes, biologics with a focus on method development and in‑depth characterization. The ideal candidate will be able to perform quality work under limited supervision, apply problem solving techniques to maintain accurate results, promote improvements, and assure a safe, stable, on‑target operation within the laboratory.

The selected candidate should possess excellent analytical, organizational and communication skills and be a self‑starter willing to work efficiently and collaboratively in a dynamic environment.

• Primary responsibility is to support the Separations and Biophysics group within Analytical Sciences.
• Be a hands‑on presence in the laboratory, supporting biophysical/biochemical assay development and qualification using HPLC and CE (must have) for various modalities (preferably biologics). LC‑MS (high‑res) experience is also desirable.
• Provide routine analytical characterization & testing support to partner groups including Upstream and Downstream PD, Formulations, and Research & Early Development (RED).
• Document experimental results in the company electronic lab notebook (Benchling), author procedures, and contribute to technical documentation (test methods, development reports).
• Actively participate in the operational aspects of the laboratory by conducting safety inspections, lab organization, ordering supplies, and performing routine equipment maintenance.
• Present scientific literature and results from ongoing studies at group meetings and other discussion forums at the company.
• Other duties as assigned.

Required Skills

• Hands‑on experience in the biotechnology industry or academic setting with a broad range of analytical techniques focused on analytical testing and characterization for proteins, peptides, and protein‑conjugates is required.
• Experience with biochemical characterization methods is required: SEC, SCX, RP‑HPLC experience is a must (Agilent/Waters/Thermo LC…