Principal Research Scientist II, Biologics Drug Product Development
Listed on 2026-01-26
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Healthcare
Medical Science, Clinical Research
Company Description
Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at Follow @abbvie on X, Facebook, Instagram, You Tube, Linked In and Tik Tok.
Job DescriptionBiologics Drug Product Development (Bio DPD), a part of Development Sciences within Abb Vie’s R&D, is a global organization that is responsible for drug product formulation and process development, and definition of the product presentation for biologics (proteins, conjugates, peptides, neurotoxins etc.) and genetic medicine (AAV, LNPs, Cell Therapy).
Abb Vie is seeking a highly motivated candidate for the position of Principal Research Scientist II, located in North Chicago, IL. We are seeking an accomplished scientist with a proven track record in biologics drug product process development, modeling, scale‑up and tech transfer. This position will be an integral part of the product development and CMC teams and will have strong collaborations with several stakeholders, including discovery research, analytical research and development, bioprocess development, combination products development, product development science and technology, pilot plants and third‑party manufacturers.
Key Responsibilities- Lead the early‑stage biologics drug product process development group in Lake County, IL
- Accountable for drug product process development, scale‑down modeling, process simulation, manufacture of technical batches, and process scale‑up and tech transfer for early‑stage biologics and sterile parenteral programs.
- Initiate and/or support scientific initiatives to drive innovation, continuously enhance capabilities and platforms, and improve business processes.
- Serve as a drug product team leader for one or more projects and represents Bio DPD in the cross‑functional Product Presentation and Device Strategy Team (PPDST) and the CMC Team.
- Effectively and timely communicate development plans, risks, and mitigation plans to stakeholders and line management.
- Support due diligence for business development opportunities.
- Manage a team of 4‑5 scientists and engineers (BSc to PhD level) including other drug product team leaders.
- Responsible for performance management, development plans, and recommendations for promotions and transfers for direct reports.
- Bachelors, Masters, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related disciplines with 16+ (Bachelors), 14+ (Masters), or 8+ (PhD) years of relevant industry experience.
- Proven ability to solve critical scientific problems.
- Strong experience with biologics (proteins, conjugates, peptides and/or neurotoxins), parenteral synthetic molecules and/or genetic medicine (AAV, LNPs, cell therapy) drug product process development.
- Extensive experience with sterile manufacturing unit operations (freeze‑thaw, compounding, mixing, filtration and filling) characterization, scale‑down models, simulation, scale‑up, technology transfer, and batch record authoring.
- Experience as CMC cross‑functional matrix team leader.
- Hand‑on experience with authoring regulatory filings for biologics and sterile parenteral products.
- People management experience.
- Biologics drug product formulation development
- Understanding of relevant cGMP and regulatory guidance for biologics and sterile parenteral products
- Experience in managing third party manufacturers of sterile parenteral products
- Experience with quality risk management and control strategies for biologics and sterile parenteral products
- Deep scientific knowledge and significant hands‑on experience with drug product process development and tech transfer
- Effectively communicates to influence without authority, drives technical excellence, and inspires continuous improvement.
- Builds strong relationships with peers and…
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