Director, Commercial Systems and Data

Immunome is a clinical‑stage targeted oncology company committed to developing first‑in‑class and best‑in‑class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting‑edge therapies, including antibody‑drug conjugate therapies. Our pipeline includes varegacestat, a late‑clinical stage GSI; IM‑1021, a clinical‑stage ROR1 ADC; and IM‑3050, a FAP‑targeted radiotherapy that recently received IND clearance.

We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.

Immunome is building the commercial systems and data capabilities required to prepare for launch and scale a high‑performing, efficient commercial organization. The Director, Commercial Systems and Data will own the strategy, roadmap, and operating model for Commercial and Field Medical CRM, data aggregation/data lake integration, and the dashboards, KPI tracking, and standardized reporting required to enable clarity, performance management, compliance, insights, and rapid decision‑making.

This leader will build a unified commercial data ecosystem grounded in accuracy, usability, compliance, predictable insights, and transparent performance—while establishing cross‑functional governance, data standards, and scalable field training to drive adoption and sustained value.

Key deliverables include CRM architecture and workflow governance with an enhancement roadmap; unified commercial data vision and strategy; data aggregator implementation and day‑to‑day operations; data alerts; role‑based CRM and analytics training; and commercial data governance strategy and SOPs.

• Develop and implement a unified commercial data vision and strategy that enables clear performance management, compliant execution, and rapid decision‑making across Sales, Marketing Operations, and Field Medical.
• Define the target‑state commercial data ecosystem (CRM, data aggregation, reporting/visualization, governance) and build a scalable roadmap aligned to launch milestones and growth.
• Translate commercial priorities into actionable system requirements, metric definitions, and data products that drive field execution and leadership visibility.

• Own Commercial and Field Medical CRM capabilities end‑to‑end, including architecture, configuration, workflows, data model, user experience, and ongoing enhancements.
• Establish CRM workflow governance, enhancement intake/prioritization, change control, release management, documentation, and communication practices.
• Drive CRM data hygiene standards and operating routines (e.g., account/HCP maintenance, activity capture expectations, required fields, and quality controls).
• Partner with Sales, Marketing Operations, and Field Medical leadership to ensure CRM supports core field workflows and evolves with business needs.
• Ensure appropriate role‑based access, auditability, and compliant use of data and workflows in partnership with Legal/Regulatory/Compliance and Medical Affairs (as applicable).

• Lead the implementation, build, and ongoing day‑to‑day operations of the commercial data aggregator and its integration into the commercial data lake.
• Oversee master data management (MDM) and identity resolution processes that enable trusted HCP/HCO and account hierarchies, including ongoing stewardship and issue resolution.
• Establish data quality monitoring, exception handling, refresh cadences, and service‑level performance expectations with vendors/partners.
• Ensure stable integrations and data flows between CRM, third‑party sources, and reporting/analytics platforms to support consistent commercial reporting.
• Deliver dashboards, KPI tracking, and standardized reporting for systems and workflows supported by this role, ensuring alignment to overall commercial reporting and performance rhythms.
• Define and maintain metric logic, reporting definitions, and data dictionaries to ensure…