Scientist II, Immunology

Anvia Therapeutics is a dynamic and innovative biotech company dedicated to developing small molecule inhibitors targeted at treating inflammatory and autoimmune diseases. We foster a collaborative environment where scientific excellence and creativity drive our mission to develop impactful medicines.

yWe are seeking a highly motivated immunology Scientist to drive hypothesis-driven in vitro immunology research in a fast-paced and innovative drug discovery environment. The successful candidate will design, develop, and execute complex cellular assay systems, including primary human immune cells, patient-derived samples, and disease-relevant cell lines to support immune pharmacology and mechanism-of-action (MoA) studies across inflammatory disease programs such as IBD, rheumatoid arthritis, and dermal inflammation

• Design and execute hypothesis-driven cellular assays to support immune pharmacology, target validation, and MoA studie
• Develop, optimize, and validate complex in vitro assay systems using primary immune cells, patient-derived samples, and disease-relevant or engineered cell line
• Perform functional immune assays including cell activation, proliferation, cytokine production, signaling, and cytotoxicity, using both primary and cell-line–based system
• Contribute to immune pharmacology assessments, including compound potency, pathway modulation, selectivity, and translational relevanc
• Apply a strong mechanistic understanding of immune and inflammatory signaling pathways to guide assay design and data interpretatio
• Utilize flow cytometry, ELISA/MSD/other cytokine/chemokine profiling techniques, protein- and signaling-based assays, and related techniques to generate high-quality, reproducible dat
• Analyze, interpret, and clearly communicate experimental results to project and leadership team
• Troubleshoot and refine experimental systems to improve robustness, scalability, and biological relevanc
• Maintain accurate experimental records using electronic laboratory notebook
• Collaborate closely with lead discovery, chemistry, translational, and external partners to advance program milestone
• Stay current with emerging immunology technologies and incorporate innovative methodologies where appropriat

• PhD in Immunology, Biology, Biotechnology, Molecular Biology, or a related field with 2+ years of relevant experien
• Hands-on experience developing and executing complex cellular assays using primary immune cells, patient-derived samples, and cell line–based syste
• Experience working with functional immune readouts, including flow cytometry–based phenotyping and signaling assays, and cytokine measurement (ELISA/MSD/othe
• Demonstrated expertise in protein-level analysis of signaling pathways, including Western blotting and related biochemical techniques used to assess pathway activation, inhibition, and mechanism of acti
• Strong understanding of cell signaling pathways relevant to immune and inflammatory biolo
• Proven ability to independently design experiments, troubleshoot assays, and manage multiple prioriti
• es. Proficiency with data analysis and visualization tools (e.g., Graph Pad Prism, Flow Jo, Exce
• l).Excellent written and verbal communication skil

• Experience supporting immune pharmacology and MoA characterization in early drug discov
• ery Background in inflammatory or autoimmune disease biology (IBD, RA, dermatology preferr
• ed).Familiarity with assay validation, quantitative potency assessment and translational biomarker analysis/ identificat
• ion.
  
  Experience working in a fast-paced, innovative biotech environm

• n Us?
  
  Be part of a passionate team making a difference in biotech innova
• tion.
  
  Collaborative and dynamic work environ
• ment.
  
  Hands-on experience with state-of-the
  - technolo
• gies.
  
  Opportunities for professional development and advance
• ment.
  
  Competitive compensation and bene

fits.
The salary range for this position is $115,000-$150,000 per year. The actual compensation offered will be based on factors such as relevant experience, education, and skills. In addition to base salary, we offer a comprehensive benefits package, including health insurance, paid time off, and retirement plan op

tions.
Anvia Therapeutics is an equal opportunity employer. We do not discriminate against any employee or applicant for employment because of race, creed (religion), color, national origin, sex (including gender identity and sexual orientation), age, disability, marital status, citizenship status, military status, genetic information, or any other characteristic protected by federal, state, or loc

al law.
Our employment decisions are based on merit, qualifications, and business needs. We are committed to providing a work environment free from discrimination, harassment, and retaliation, and we undertake affirmative action efforts to promote equal opportunity for all employees and app

licants.