Financial Commitments Manager

The Manager of Financial Commitments supports the management of external and internal expenses for TB Alliance’s multi-year Research and Development portfolio. This role is responsible for tracking project-related financial commitments, supporting forecasting and milestone payments, and ensuring accurate expense reconciliation. The position is hands-on and collaborative, working across the organization with R&D, Human Resources and Finance teams.

• Support Clinical Development and Finance leadership during vendor selection and contract review and screening processes.
• Track financial commitments, payment milestones, and expenses across R&D projects throughout the project lifecycle.

• Serve as back up for the invoices review process to ensure accuracy, appropriate documentation, and correct project and general ledger coding.
• Assist with month-end, quarter-end, year-end close activities and external audit process.
• Prepare routine and ad-hoc financial reports related to R&D spending and commitments.
• Manage grant management funding forms, inquiries and reporting.

• Manage banking activities, including preparing wire transfers and coordinating with approvers.
• Prepare bank and investment accounts reconciliations.
• Manage payroll, including but not limited to bi-monthly payroll processing, allocations, reconciliations, and tax filings.
• Manage the retirement plan funding, quarterly and year-end true-up reconciliations.
• Manage the annual retirement plan non-discrimination testing, filing of 5500 and related schedules.
• Manage the administrative aspects of insurance renewals and other finance operational activities, as assigned.

• Follow and maintain finance policies, procedures, and documentation related to financial commitments.
• Identify opportunities to improve efficiency, accuracy, and use of financial systems; demonstrate willingness to learn new tools and processes.
• Ensure full adherence to applicable GxP and regulatory standards. Maintain alignment with annual GxP and regulatory training requirements.

• Bachelor’s degree in accounting, Finance, Business, or a related field.
• 5–10 years of relevant accounting, finance, or project finance experience.
• Experience supporting pharmaceutical R&D, clinical research, or grant-funded environments strongly preferred.
• Experience with Net Suite desired.
• Strong attention to detail with solid analytical and organizational skills.
• Comfortable working with financial systems and spreadsheets; interest in technology and process improvement.
• Ability to work collaboratively in a mission-driven, global organization.

TB Alliance is the recognized leader in accelerating the development and adoption of urgently needed new anti-tuberculosis (TB) drugs. The transformative BPaL/M regimens have become the gold standard for drug-resistant TB treatment, available at affordable pricing in more than 150 countries worldwide and approved by regulatory agencies in 28 countries.

TB continues to cause more deaths worldwide than any other infectious disease and disproportionately impacts marginalized populations as the disease is concentrated in lower- and middle-income countries and in patient populations in the lowest economic strata. The World Health Organization (WHO) reports an estimated patient population of 10 million annually with active TB, of which 410,000 have drug-resistant forms of the disease.

In addition, over 1.5 billion people are infected with the TB bacillus, forming the reservoir for the development of active TB.

Despite the high degree of unmet need worldwide, lack of commercial viability severely limits commercial interest in this disease area and treatment improvements are largely dependent on financial subsidization through public sector and private sector funding. TB Alliance was established to fulfill the need for greatly improved TB treatment, deploying a unique not-for-profit operating model characterized by a small core of highly experienced internal staff with…