NS Production Technician - Downstream

Overview

The Production Technician III plays a vital role in executing cGMP manufacturing activities within a regulated biologics environment, focusing primarily on Downstream Purification. This position involves independently carrying out complex processing tasks, aiding in troubleshooting, resolving deviations, and acting as a technical resource for junior technicians during night shift operations. The role requires working night shifts on a 12-hour, 2-2-3 schedule.

• Execute downstream purification operations in accordance with batch records, SOPs, and cGMP requirements.
• Operate and monitor chromatography systems using Unicorn software (e.g., ÄKTA skids), including method execution, alarms, and system performance.
• Perform purification unit operations such as chromatography, buffer preparation, solution transfers, and filtration.
• Conduct in-process sampling and analyses (e.g., pH, conductivity, UV) and document results per GDP standards.
• Perform equipment setup, changeover, CIP/SIP, and line clearance activities.
• Troubleshoot process and equipment issues and support deviation investigations and corrective actions.
• Train and mentor Production Technician I and II personnel.
• Maintain compliance with safety, environmental, and quality regulations.

• Advanced experience in downstream purification, specifically chromatography using Unicorn software.
• Strong understanding of cGMP manufacturing and electronic or paper batch record execution.
• Ability to work independently on night shift and support continuous operations.
• Experience in biologics, biotech, or pharmaceutical manufacturing.

• High School Diploma or GED with 2 years of related experience, or Associate’s degree in life science with 0–1 years of related experience, or equivalent military training or experience.
• Preferred: 2+ years of experience in a cGMP manufacturing environment.
• Preferred:
  Bio Work Certificate.

The work environment requires physical capabilities such as wearing respiratory protection, discerning audible cues, performing tasks requiring 20/20 corrected vision, including color distinction, and the ability to ascend and descend ladders, scaffolding, or ramps. The position involves standing or sitting for prolonged periods, performing repetitive motions with wrists, hands, and fingers, and lifting up to 33 lbs. The role operates in various temperature conditions (0°F–100°F), may involve working in small or enclosed spaces, and at heights greater than 4 feet.

The work does not routinely require outdoor activities or operating powered industrial trucks.

This is a Contract position based out of Morrisville, NC.

The pay range for this position is $25.00 - $30.00/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccom for other accommodation options.