Director of Operations

Job Details

Updated: December 10, 2025
Location: Morrisville, NC, United States
Job :-OTHLOC-1500-2

DNE-2DR

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full‑Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

WORK HERE MATTERS EVERYWHERE

Discover what our 29,000 employees, across 110 countries already know:

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

The Director of RWLP Operations is a strategic, client‑facing leader responsible for driving operational excellence across real‑world and late‑phase research portfolios. This role ensures successful delivery of peri‑ and post‑approval studies while fostering account growth and long‑term client partnerships. Acting as a subject‑matter expert and operational strategist, the Director provides end‑to‑end oversight—from RFP/proposal development to portfolio execution—ensuring integrated, cost‑effective solutions aligned with client objectives.

Key responsibilities include:

• Leading cross‑functional teams to deliver complex, global RWLP programs on time and within budget.
• Overseeing all aspects of assigned client accounts, including governance, risk management, financial performance, and strategic planning.
• Partnering with internal and external stakeholders to identify evidentiary needs and deliver tailored operational solutions.
• Ensuring alignment of delivery with regulatory standards (ICH, GCP, GPP) and Syneos Health SOPs.
• Supporting business development through proposal strategy, bid defenses, and capability presentations.
• Driving operational efficiency, quality, and innovation through lessons learned, process improvement, and cross‑BU collaboration.
• This role requires strong real‑world research acumen, proven operational leadership, and a commercial mindset.
• Ideal candidates will bring:
• 10–12 years of clinical research experience, with 8–10 years in RWLP.
• Direct experience with large‑scale RWLP programs and client portfolio oversight.
• Strong financial and contract management skills.
• Prior CRO/pharma experience in cross‑functional, global environments.
• Excellent communication, team leadership, and stakeholder management capabilities.
• The Director may have direct reports and is expected to travel up to 25% of the time.

The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401(k), eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work.

Syneos complies with all applicable federal,…