Senior Global Project Head, Neurology Development

Overview

Job Title: Senior Global Project Head, Neurology Development

Location: Cambridge, MA;
Morristown, NJ

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. The Sr GPH, Neurology Development leads early development activities in Neurology Development. The role shapes strategy and manages execution, working closely with the Therapeutic Area heads to build and renew the early portfolio in Neurology.

This role focuses on multiple projects from IND-enabling studies to first-in-human studies and proof-of-concept trials, with potential transition to lead a later-stage program in some cases. New programs come from internal research or in-licensing. The Early Development GPH contributes to project selection and drives execution until proof of concept is achieved.

Sanofi is pursuing disease-modifying treatments for CNS diseases including MS, CIDP, Alzheimer’s Disease, Parkinson’s Disease, ALS, and other neurodegenerative conditions, with a focus on Alzheimer's Disease for this role. The Sr GPH collaborates with internal and external stakeholders across preclinical, regulatory, and commercial functions to influence disease area strategy and operations.

Success requires scientific excellence, integrative thinking, and strong interpersonal skills. The Sr GPH reports to the TA Head, NOD, and will join at a point of opportunity to build and influence the group. This role requires innovation, stakeholder engagement, and key decision-making across internal and external partners. The Sr GPH leads global project teams (GPT) and participates in strategic planning and oversight of clinical activities in their area.

Responsibilities include interaction with regulatory authorities, protocol approvals, informed consent documents, clinical study reports, product labels, and communication strategy. Travel and expense management are included, and interaction with opinion leaders and consultants is expected.

Sanofi’s Key Therapeutic Areas include Immunology, Neurology & Ophthalmology Development (NOD), Rare Diseases, and Vaccines. The NOD TA includes Neuroimmunology, Neurodegeneration, and Ophthalmology, with modalities spanning Small Molecules, Biologics, and Gene Therapy. Sanofi maintains an internal research team and the Genomic Medicine Unit (GMU) to build the future pipeline.

About Sanofi
We’re an R&D-driven, AI-powered biopharma company focused on improving lives through science and a strong pipeline.

Scientific and Technical Expertise

• Has and maintains deep scientific, technical, and clinical expertise in Neurology
• Deep expertise in neurodegenerative diseases, especially Alzheimer's disease, is preferred
• Understands and stays current with preclinical, clinical pharmacology, and other data related to the molecule of interest
• Critically reads and evaluates relevant medical literature with deep understanding of data and competitive status
• Maintains visibility within the therapeutic area to credibility with internal and external stakeholders
• Oversees development planning, execution, and budget
• Owns the overall program strategy and leads the international cross-functional team to meet objectives
• Participates in lifecycle management strategy planning with marketing teams
• Proposes strategies for interactions with health authorities
• Establishes project goals aligned with resource allocation and objectives
• Responsible for generating support and implementation of clinical studies
• Ensures operational plans are integrated across functions
• Responsible for annual budget deliverables

Management and Career Development

• Ensures team members are qualified and trained, including compliance training for direct reports
• Works cross-functionally to select appropriate team members
• Sets team objectives and develops individual performance and development goals

Regulatory Responsibilities

• Ensures clinical data meet regulatory standards
• Supports registrations, label submissions, and modifications
• Manages Advisory Committee preparation and participation
• Ensures timely submission and dissemination of…