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Research Associate - Precision Oncology of Gastrointestinal Cancers

Job in Monrovia, Los Angeles County, California, 91017, USA
Listing for: City of Hope
Full Time position
Listed on 2026-01-23
Job specializations:
  • Research/Development
    Clinical Research, Research Scientist, Medical Science
  • Healthcare
    Clinical Research, Medical Science
Job Description & How to Apply Below
Position: Research Associate I - Precision Oncology of Gastrointestinal Cancers

Overview

Join the transformative team at City of Hope, where we are changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope's growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago, and Phoenix.

Our dedicated and compassionate employees are driven by a common mission:
To deliver the cures of tomorrow to the people who need them today.

We seek a Research Associate within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair of the Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences at City of Hope Comprehensive Cancer Center. Our research focuses on translational studies of the genomic and epigenomic characterization of gastrointestinal cancers (GI), including colorectal, pancreatic, and gastric cancers.

Key

research topics
  • Developing ctDNA and cfRNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis, and predictive responses to various therapies.
  • Study the epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs).
  • The genetic basis of early-onset and familial/hereditary colorectal cancers.
  • The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies.
  • The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers.
  • As a successful candidate, you will
    • Maintain various aspects of lab management, including maintenance and upkeep of reagent and clinical specimen inventories, ordering, lab safety, and regulatory tasks.
    • Ensure that all laboratory activities comply with procedures by utilizing safety procedures and guidelines in handling, storage, and disposal of bio-hazardous, infectious, and toxic material.
    • Perform a variety of routine and non-routine laboratory research experiments and record and validate results for accuracy and completeness.
    • Perform Cancer Genetics and Epigenetics techniques and general lab maintenance that assists in conducting an Investigator's Research Project.
    • Be responsible for accurately recording work performed, including results and methodology.
    Qualifications

    Your qualifications should include:

    • Bachelor's or master's degree; master's degree preferred.
    • Two years of laboratory experience with a bachelor's degree or 3 years of related research/laboratory experience with a master's degree.
    • Assist and perform various molecular biology techniques, such as tissue culture, flow cytometry (analysis), and molecular tests, according to the Laboratory's Standard Operating Procedures.

    City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity, and inclusion, please .

    To learn more about our Comprehensive Benefits, please .

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    Position Requirements
    10+ Years work experience
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