Technologist III, Downstream Manufacturing - Biologics - Eurofins CDMO Alphora, Inc.

We are seeking a highly skilled Technologist Level III – Downstream Manufacturing to join our cGMP Manufacturing team. In this hands‑on and technically focused role, you will play a pivotal part in producing novel biologics and therapeutics while ensuring full compliance with cGMP standards.

You will support and execute downstream operations—including chromatography, TFF, filtration, nanofiltration, and bioconjugation—while also contributing to process transfer, scale‑up, equipment qualification, and documentation. This position is ideal for someone who thrives in a fast‑paced, regulated environment and enjoys combining technical depth with operational excellence.

The Technologist III - Downstream Manufacturing, is responsible for playing a crucial role in the cGMP manufacturing of novel biologics and therapeutics as well as ensuring cGMP compliance of all manufacturing areas. The successful candidate will support manufacturing activities that involve downstream processing steps including chromatography, tangential flow filtration (TFF), filtration, and nanofiltration as well as bioconjugation. The ideal candidate will also play key roles in the preparation of cGMP documentation such as batch records, and CQV protocols in addition to aiding activities such as process transfer and scale up as needed.

At Eurofins CDMO Alphora Inc., our mission is to harness the power of biotechnology and bioprocessing to create innovative complex medicines that will improve the lives of patients worldwide. With a dedicated team of experienced scientists, motivated technologists, and state-of-the-art process development (PD) facility, we are thrilled to be at the forefront of the biopharmaceutical CDMO industry in Canada. Join us on this exciting journey as we push the boundaries of scientific research and provide hope to our most vulnerable.

What You’ll Do

As a Technologist III, you will be a key technical contributor and manufacturing leader supporting downstream cGMP operations:

Downstream Processing & Execution

• Serve as a primary technical contact for transferring processes from Process Development (PD) into cGMP manufacturing.
• Operate advanced purification equipment, including AKTA Ready Gradient, AKTA Ready Gradient XL, AKTA Readyflux, and AKTA Readyflux XL.
• Execute downstream processing steps such as chromatography, TFF, depth filtration, nanofiltration, viral inactivation, and protein bioconjugation.
• Perform in‑process sampling and basic analytical tests within the manufacturing suite.

Quality, Compliance & Documentation

• Assist in technical investigations, perform Root Cause Analysis (RCA), and prepare thorough deviation reports and CAPA plans.
• Write and review batch records, SOPs, and cGMP documentation.
• Author and execute commissioning, qualification, and validation (CQV) protocols.
• Ensure facility and equipment logbooks are completed accurately and in compliance with SOPs.
• Maintain a constant state of inspection readiness for internal audits, client visits, and regulatory inspections; serve as an SME when required.

Cross‑Functional Collaboration

• Work closely with Upstream Processing, QA, and QC to coordinate smooth material handoffs and timely sample testing.
• Partner with QC Raw Materials on material release and inventory management.
• Order consumables, raw materials, and equipment; coordinate preventive maintenance and equipment calibration.

Operational Excellence & Safety

• Support suite cleaning, room changeovers, and overall GMP cleanliness according to CL2 and cGMP expectations.
• Ensure junior staff follow PPE requirements and exhibit proper ergonomic practices, especially when handling biohazardous materials or heavy equipment.
• Promote a culture of safety, quality, and continuous improvement on the manufacturing floor.

Why Work Here

Join a team where your technical expertise and hands‑on contributions directly impact the production of cutting‑edge therapeutic products.

⭐ Meaningful, High‑Impact Work

Your daily efforts contribute to the manufacturing of novel biologics with real‑world therapeutic potential.

⭐ Advanced Technology & Skill Development

Operate state‑of‑the‑art purification platforms and gain…