Director, Alliance Strategy & Management

Director, Alliance Strategy & Management

About Summit:
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people.

Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi:
Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR‑mutated, locally advanced or metastatic non‑squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi‑3:
Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first‑line metastatic NSCLC.

HARMONi‑7:
Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first‑line metastatic NSCLC.

HARMONi‑GI3:
Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

The Director, Alliance Strategy & Management leads the performance and strategic evolution of the company’s external partnerships. This role ensures that alliances deliver on their scientific, clinical, and commercial potential by fostering trust, transparency, and operational excellence across collaborations. Working closely with the Department Head and Business & Strategy colleagues, this leader is a key contributor to product strategy & combinations strategy with ownership of operational integration with partners, plus maintaining oversight.

This role interfaces with internal & external partners, driving alignment, accelerating joint OKR achievement, resolving issues, and unlocking long‑term value. The capabilities to actively build strategy, deliver operational plans and execute the details is essential. The ideal candidate brings experience in hands‑on R&D and product management, alliance management, strong cross‑functional leadership, and a proactive mindset to maximize the impact of external innovation.

This leader will have end‑to‑end accountability for multiple external collaborations.

Alliance Governance & Oversight

Lead collaboration planning, activation and execution; to include study start‑up, joint committees, governance forums, and operational reviews to ensure strategic alignment and execution across partnered programs.

Relationship Management

Serve as point of contact for alliance partners, building trust, facilitating communication, and resolving issues with speed and diplomacy; a face and voice of the company externally.

Milestone & Performance Tracking

Monitor progress against contractual milestones, deliverables, and KPIs; ensure timely reporting and actively solving issues.

Strategic Integration & Value Realization

Collaborate with internal teams to integrate alliance activities into broader portfolio and pipeline strategies, ensuring long‑term value creation across tumors, indications and regions.

Cross‑Functional Coordination

Partner with R&D, Clinical, Regulatory, Legal, and Commercial teams to align on joint program execution, decision‑making, and resource planning.

Develop and implement alliance management…