Senior Director, Information Technology

Senior Director, Information Technology page is loaded## Senior Director, Information Technology locations:
US - California - Menlo Parktime type:
Full time posted on:
Posted Yesterday job requisition :
JR100788

Title:

Senior Director, ITPacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems.  Our mission is to enable the promise of genomics to better human health. Genomics is core to all biological processes, and our advanced genomics tools provide scientists and clinical researchers the insights to better understand biology and health.  

We are now entering the century of biology and genomics is at the heart of the next revolution.  Become part of the new paradigm in gene sequencing and help shape the future of genomic study by joining the Pac Bio team.

The Senior Director, IT is responsible for leading the global IT organization at Pac Bio, encompassing teams that support enterprise, financial, manufacturing, and R&D information systems. This is a highly visible, cross-functional leadership role that partners closely with executive leadership and stakeholders across the company to enable business strategy, operational excellence, and innovation through secure, scalable, and compliant technology solutions.

This role is ideal for an experienced IT leader with a strong background in life sciences and public-company environments, deep expertise in regulated systems, and a demonstrated ability to balance strategic vision with operational execution. Cybersecurity, risk management, compliance and management of IT operations and business applications teams are core responsibilities of this role.

Responsibilities:
* Lead, develop, and scale a high-performing IT organization, including managers and senior technical leaders.
* Foster a culture of accountability, service excellence, security awareness, and continuous improvement.
* Define and execute a multi-year IT strategy and technology roadmap aligned with Pac Bio’s business objectives.
* Partner closely with Finance, Manufacturing, R&D, Quality, Legal, and Commercial teams to support business needs and continually improve operational efficiency.
* Own Pac Bio’s cybersecurity strategy, posture, and operations, including prevention, detection, response, and recovery.
* Ensure compliance with ISO 27001, SOX, and other applicable regulatory and audit requirements, including leading, coordinating, and interfacing directly with internal and external SOX auditors.
* Lead IT risk management, security governance, incident response planning, and third-party risk management.
* Establish and maintain security policies, standards, and controls across infrastructure, applications, and data.
* Partner with internal and external auditors to support audits and remediation activities.
* Ensure IT systems supporting regulated processes comply with validation and quality requirements (e.g., GxP).
* Own IT governance frameworks, including SDLC, change management, access controls, and data governance.
* Maintain audit readiness and documentation across systems and processes. Oversee enterprise architecture, application portfolio management, and system lifecycle planning.
* Lead the operation and evolution of hybrid infrastructure, including on-premises and cloud environments.
* Support high-performance computing (HPC) and large-scale storage platforms for R&D and data-intensive workloads.
* Drive reliability, scalability, and performance of mission-critical systems.
* Drive modernization initiatives, including cloud adoption, automation, and legacy system rationalization.
* Own the IT budget, forecasting, and cost optimization initiatives.
* Manage strategic vendor relationships, system integrators, and managed service providers.

Required Qualifications:

* Bachelor’s degree in Information Systems, Computer Science, Engineering, or a related field; advanced degree preferred.
* 12+ years of progressive IT experience, including significant leadership at the director or senior director level.
* Experience in a public company, preferably…