Translational Research Scientist, Oncology

Overview

Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators who transform healthcare. At Billion To One , transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: scientists, engineers, sales professionals, and visionaries united by a commitment to changing the standard of care in prenatal and cancer diagnostics.

This is where cutting-edge science meets human compassion, and every innovation helps remove fear of the unknown in some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong.

We are looking for a Translational Research Scientist, Oncology to join a fast-growing team. This role bridges the gap between our molecular assays and clinical outcomes, owning the analysis of clinical data, developing statistical models to validate our Northstar oncology products, and shaping the design and execution of clinical studies. This is a full-time onsite position reporting to the Associate Director of Oncology Translational Research
.

• Clinical Data Orchestration:
  Lead the cleaning, preprocessing, and integration of complex clinical datasets with molecular informatics to ensure high-quality inputs for downstream analysis.
• Statistical Modeling:
  Develop and implement robust clinical-statistical models, including Cox Proportional Hazards (Cox PH), Kaplan-Meier estimates, and logistic regression, to evaluate clinical utility and patient outcomes.
• Clinical Study Support:
  Provide data-informed recommendations for the design and analysis of clinical studies, ensuring protocols are optimized to demonstrate the validity of our oncology assays.
• Insights Generation:
  Analyze assay performance within clinical cohorts and contribute to high-impact publications and regulatory submissions that establish the standard of care.
• Cross-Functional Collaboration:
  
  Partner with R&D scientists to translate laboratory breakthroughs into clinical insights and collaborate with clinical trial operations to monitor study progress. Partner with numerous internal and external teams to drive scientific results.
• Communication:
  Present complex statistical findings and clinical insights to internal stakeholders, clinical investigators, and at scientific conferences.

• PhD in Biostatistics, Bioinformatics, Cancer Biology, Epidemiology, or a related quantitative field.
• 2+ years of experience working with clinical datasets and conducting survival analysis (specifically Cox PH and time-to-event modeling).
• Proven track record of analyzing and cleaning large-scale clinical data from trials or electronic health records (EHR).
• Fluency in Python or R for statistical computing and data visualization.
• Deep understanding of oncology and the clinical applications of NGS-based diagnostics.
• Excellent communication and presentation skills, with the ability to explain complex statistical concepts to non-experts.

• Experience in a fast-paced start-up environment.
• Experience working in a regulated environment (MolDX or FDA-regulated study designs).
• Familiarity with clinical data standards (e.g., CDISC/SDTM).
• Experience with SQL and cloud-based data environments (S3/AWS/GCP).

• Working alongside brilliant, kind, passionate and dedicated colleagues in an empowering environment toward a global vision for transformative molecular diagnostics.
• Open, transparent culture with weekly Town Hall meetings.
• The ability to indirectly or directly change the lives of hundreds of thousands of patients.
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%.
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%).
• Supplemental fertility benefits coverage.
• Retirement savings program including a 4% Company match.
• Paid time off increases with tenure.
• Latest hardware and on-site facilities, including daily on-site lunches.
• A variety of campus perks (state-of-the-art gym, restaurant) and free on-site EV charging.

At Billion To One , we offer a total compensation package including base pay, equity options, and a corporate bonus program, on top of industry-leading benefits. For this position, the total compensation package is $202,625 per year, with a base pay range of $126,721 - $147,841 per year.

Billion To One  is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. For more information about how we protect your information, review our Privacy Policy.

Billion To One  is a next-generation molecular diagnostics company on a mission to make…