Investor Relations Manager

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit

The Investor Relations Manager will be responsible for day-to-day execution of investor relations activities. Reporting to the Director, Investor Relations, this role focuses on preparing investor materials, managing recurring reporting and communications, supporting earnings and investor events, and maintaining accurate, compliant disclosure. The position requires strong attention to detail, financial analysis skills, and the ability to operate effectively in a public-company environment with tight deadlines.

This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.

At our Menlo Park campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.

• Coordinate logistics for earnings calls, investor meetings, conferences, and non-deal roadshows; prepare briefing materials for executives ahead of investor and analyst meetings.
• Prepare quarterly and annual earnings materials, including press releases, earnings scripts, investor presentations, and supporting materials.
• Develop and maintain detailed earnings Q&A documents based on business progress, financial results, and company guidance.
• Support preparation of materials tied to SEC filings, including quarterly and annual filings, and other public disclosures, in coordination with Finance, Legal, Corporate Communications, and other teams.
• Analyze quarterly performance, key operating metrics, and trends to support investor messaging; track analyst models, consensus estimates, and forecast changes.
• Maintain calendars, timelines, and checklists to ensure on-time execution of all investor relations deliverables.
• Maintain records of investor interactions, feedback, and follow-ups.
• Ensure accuracy, consistency, and compliance across all investor relations content.
• Monitor stock performance, trading activity, and ownership changes.
• Support ad hoc investor inquiries and requests in a timely and compliant manner.
• Assist with special projects such as capital markets or strategic transactions, roadshows, and other initiatives, as needed. These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list.
• They may change at the company’s discretion.

• Bachelor’s degree in Finance, Accounting, Economics, Business, or a related field.
• 6 years of experience in investor relations, equity research, investment banking, or corporate finance.
• Strong working knowledge of capital markets, financial statements, and the earnings process.
• Very strong attention to detail and ability to manage deadlines.
• Strong written communication skills, with experience drafting investor-facing materials.
• Experience supporting a publicly traded company or formally researching, covering, or advising a publicly traded company.
• Familiarity with SEC reporting requirements and…