Senior Bioinformatics Analyst - Center of Excellence in Neuro-Oncology Sciences

Job Description

The Senior Bioinformatics Analyst is responsible for designing, developing, and operating structured databases and analysis pipelines to optimize usage and accessibility. Manages data integration and coordinates other efforts related to infrastructure with minimal supervision.

The Northcott Lab within the Center of Excellence in Neuro-Oncology Sciences (CENOS) is seeking a highly motivated Senior Bioinformatics Analyst. The CENOS is a collaborative translational research program with a mission to improve survival and morbidity for children with brain tumors. Through application of cutting‑edge molecular approaches to unique and data‑rich cohorts, members of this program efficiently translate laboratory findings into clinical practice and treatment innovations.

The successful candidate will contribute to the management, usage, and accessibility of unprecedented multi‑omics datasets obtained from children with malignant brain cancer. Through application of structured/unstructured databases, storage and integration of large multi‑modal datasets, including bulk, single‑cell, and spatial profiles, we aim to derive novel insights with real‑world clinical implications.

• Work closely with bioinformatics personnel within the CENOS to play a role in exciting collaborations, both within St. Jude and with prominent external collaborators.
• Execute and troubleshoot data storage, management, and integration strategies independently.
• Communicate effectively with the PI and collaborators across diverse disciplines.
• Thrive in a highly collaborative team environment.

• A Master's degree in computer science, bioinformatics, computational biology, and/or data science.
• Minimum 1+ years of relevant experience.
• Experience in the development, implementation, and maintenance of relevant databases or data warehouse.
• Experience developing prototypes for cloud portals and visualization tools, and programs for the analysis of data within databases.
• Experience developing web services to query the database.
• Experience with genomic datasets (e.g., whole‑genome/exome sequencing, RNA‑seq, ATAC‑seq, ChIP‑seq/CUT&RUN, Hi‑C, DNA methylation, single‑cell/nucleus RNA‑seq, spatial transcriptomics, and quantitative proteomics).
• Experience in programming querying languages.
• Experience in at least one programming or scripting language, preferred.

• Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field.
• Master's degree preferred.

• Minimum 4+ years of relevant experience.
• Experience Exception:
  Master's degree and 1+ years of relevant experience.
• Experience in at least one programming or scripting language and at least one statistical package, with R preferred.

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. A reasonable estimate of the current salary range is $78,000 - $139,360 per year for the role of Senior Bioinformatics Analyst - Center of Excellence in Neuro-Oncology Sciences.

St. Jude is an Equal Opportunity Employer.

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