Manager - Scientific Research

Job Description

We are seeking a Manager of Scientific Research to manage the cell line creation service line within the Center for Advanced Genome Engineering (CAGE).

There's a reason St. Jude Children's Research Hospital is consistently ranked on Glassdoor's "Best Places to Work" list. Actually, there are more than 5,500 reasons. At our world-class pediatric research hospital, every one of our 5,500 professionals shares our commitment to making a difference in the lives of the children we serve. There's a unique bond when you are part of a team that will stop at nothing to advance the treatments and cures of pediatric catastrophic diseases.

The result is a collaborative, positive environment where all employees, regardless of their role, receive the resources, support, and encouragement to advance and grow their careers.

Facilitate investigator-initiated genome editing projects using CRISPR Technology
Perform independent R&D to evaluate and develop new genome editing techniques
Assist the gene and cell therapy programs e Children's Research Hospital

As Manager, you will oversee a dynamic team of researchers, drive operational excellence, and foster a culture of collaboration and innovation. You will ensure projects run efficiently, resources are optimized, and scientific goals are met with the highest standards of quality and service.

• Lead and manage a team of at least 3 scientific staff, providing mentorship and professional development
• Develop and track performance metrics to enable data-driven decision-making
• Manage vendor interactions and assist in budgetary planning and decisions
• Partner with investigators to design and implement genome editing strategies
• Oversee day‑to‑day operations of genome engineering projects and ensure timely delivery
• Drive process improvements and champion continuous improvement across workflows
• Maintain a service‑oriented approach to support institutional research needs
• Represent the team in meetings and communicate progress to leadership
• Foster a positive, inclusive, and high‑performance culture

• Extensive experience with cell culture (experience with iPSC, ESC, or HSCs a plus)
• Strong knowledge of molecular biology and genome editing techniques (CRISPR experience preferred)
• Excellent organizational, communication, and problem‑solving skills
• Experience with project management and resource allocation
• Proven ability to inspire, motivate, and develop teams
• Track record of managing complex workflows and delivering results
• Takes initiative and accountability for outcomes
• Thrives under pressure and can prioritize tasks based on team needs
• Excited by challenges and committed to staying on the cutting edge of science
• Dedicated to supporting investigators and advancing institutional goals
• Take pride in a job well done and instills that mindset within the team
• Demonstrated experience directly managing a multi‑person team, including responsibility for hiring, and performance management.
• Proven track record of developing staff through mentorship, professional growth opportunities, and strategic team‑building initiatives.

• Bachelor's degree in a relevant scientific discipline is required.

• 7+ years of experience in relevant technical field (industry or academia) is required with a Bachelor's degree.
• 5+ years of experience in relevant technical field is required with a Master's degree.
• 2+ years of experience in relevant technical field is required with a PhD.
• Experience managing at least 1-2 people preferred.
• Extensive experience leading projects/processes end to end including resource planning and management, and communication and collaboration with internal cross‑functional teams and external partners preferred.
• Experience leading and mentoring teams preferred.
• Proven performance in earlier role/comparable role.

Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude…