Vice President, Direct Response

At ALSAC you do more than make a living; you make a difference. We like people who are different…because we’re different, too. As one of the world’s most iconic and respected nonprofits, we know what it’s like to stand out. That’s why we’re looking r background, perspective, and desire to make an impact set you apart. As we work to help St.

Jude cure childhood cancer, we're calling on the game‑changers, innovators and visionaries to join our family. Not just for the kids of St. Jude, but also for you. Because at ALSAC, we develop and celebrate our employees. So, bring your whole, authentic self and become part of our shared mission:
Finding cures. Saving children.®

The Vice President, Direct Response serves as the enterprise executive responsible for leading, modernizing, and scaling one of the organization's most critical revenue engines. This role oversees a $400M+ revenue and expense portfolio and drives transformational growth through donor acquisition, retention, and long‑term loyalty across large-scale direct mail and multi‑channel direct response programs.

This VP establishes and executes the long‑term strategic vision for Direct Response—reimagining traditional direct mail approaches through audience‑led planning, data‑driven optimization, innovation, and full‑funnel integration. The role carries broad enterprise influence, shaping cross‑channel donor strategies and aligning Marketing, Creative, Digital, Analytics, FP&A, and Development teams around a unified audience‑centric roadmap.

A people‑first leader, the VP will build, develop, and inspire a high‑performing, diverse team of marketers, analysts, creatives, and operational experts while fostering a culture grounded in inclusion, transparency, accountability, and operational excellence. This executive is a strategic thinker with strong financial discipline, exceptional communication skills, and a proven ability to drive large‑scale change and breakthrough performance.

• Deep Direct Response & Direct Mail Expertise:
  Mastery of large‑scale donor acquisition and retention programs with deep experience in direct mail strategy, segmentation, testing, and data‑driven optimization.
• Strategic Leadership & Vision:
  Ability to define the future‑state strategy of Direct Mail within a multi‑channel ecosystem—evolving traditional approaches, modernizing systems, and driving organizational transformation.
• Enterprise Influence & Cross‑Functional Partnership:
  Leads alignment across Marketing, Creative, Digital, Analytics, FP&A, Development, and key external partners. Influences enterprise donor strategy and drives cross‑channel cohesion.
• Financial & Operational Management Excellence:
  Proven success managing multimillion‑dollar P&Ls, forecasting accurately, optimizing budgets, and elevating operational performance and vendor ecosystems.
• Executive‑Level Communication:
  Capable of translating complex strategies into compelling narratives for Boards, executive teams, cross‑functional leaders, vendors, and external partners.
• People Leadership & Talent Development: A leader of leaders with a track record of growing high‑performing teams, cultivating leadership pipelines, and building inclusive, engaged, high‑accountability cultures.
• Change Leadership & Modernization:
  Experienced leading organizations through modernization of processes, technology, data, testing frameworks, and audience‑led planning.
• Operational Rigor & Process Optimization:
  Focused on operational excellence through workflow redesign, forecasting improvement, automation, and performance measurement discipline.

• Executive Leadership of Direct Response Strategy
• Serves as a senior member of the Direct Response leadership team and key contributor to enterprise donor strategy.
• Defines and evolves the long‑term strategic vision for Direct Mail and Direct Response.
• Provides high‑level thought leadership for list strategy, segmentation, cultivation, retention, and donor loyalty.
• Positioned to support or step into other Direct Response leadership functions when needed.
• Drives Transformation & Channel Evolution
• Leads the long‑term strategic planning and…