Senior Director, R&D Data Science & Digital Health RWE), Therapeut

Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), Across Therapeutic Areas J&J Family of Companies
• Mcallen, TX, US

Johnson & Johnson Innovative Medicine is recruiting for Senior Director, R&D Data Science & Digital Health, Real-World Evidence (RWE), across therapeutic areas.

The primary location for this position is flexible Titusville, NJ;
Raritan, NJ;
Spring House, PA;
Cambridge, MA; or San Diego, CA.

J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, immunology, neuroscience, cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market from patients to practitioners and from clinics to hospitals.

The R&D Data Science & Digital Health, Real-World Evidence (RWE) team at J&J Innovative Medicine is dedicated to developing innovative evidence solutions and critical insights through diverse data sources, including RWD, trial data and emerging innovative data sources, to support clinical programs and regulatory decision-making.

We are seeking a visionary Senior Director to lead Real-World Evidence (RWE) strategy and execution across therapeutic areas (xTA). This role will be pivotal in shaping the future of RWE at the organization - driving internal/external collaboration, advancing regulatory-grade evidence generation, and elevating our scientific leadership both internally and externally.

The successful candidate will partner closely with senior leaders across R&D and commercial to build an integrated, agile, and forward-thinking RWE ecosystem. This includes leading strategic initiatives, influencing regulatory policy, and representing organization as a thought leader in the global RWE community.

Key Responsibilities

• Define and execute the RWE initiatives across therapeutic areas, ensuring alignment with long-term organizational goals.
• Lead cross-functional RWE committees and foster high-impact partnerships with internal and external stakeholders.
• Shape and elevate the enterprise-wide RWE ecosystem through innovation, governance, and capability building.
• Serve as a strategic advisor on regulatory-grade evidence generation and policy shaping.
• Lead preparation and presentation of scientific data packages for regulatory submissions and agency interactions.
• Represent J&J in external forums to influence RWE standards and regulatory expectations.
• Chair the Methodology Review Board (MRB) and oversee a portfolio of high-impact RWE projects.
• Establish best practices for novel study designs and implementation.
• Promote continuous learning and innovation in emerging RWE methodologies and technologies.
• Develop frameworks and tools to scale evidence generation and accelerate delivery.
• Champion a culture of scientific rigor, collaboration, and execution excellence.

Required qualifications:

• Ph.D. or Master's in epidemiology, biostatistics, outcomes research, health policy, or related field.
• 10+ years of relevant experience in biopharma, RWE consulting, or healthcare industries.
• 7+ years of experience as a people manager.
• Proven expertise in data extraction, cleaning, and analysis; strong grasp of advanced statistical methods.
• Experience with diverse data sources (EHR, claims, registries, trial data, digital health).
• Strong communication skills, with the ability to effectively engage both technical and non-technical stakeholders.
• Proven leadership and influencing capabilities, with a track record of inspiring teams and driving cross-functional alignment.
• Highly motivated and intellectually curious, with strong executional rigor and a passion for solving complex challenges.
• Proficiency in R, Python, or SQL.

Preferred qualifications:

• Expertise in regulatory-grade evidence generation and regulatory engagement.
• Strong leadership in cross-functional initiatives and ability to influence without authority.
• Subject matter expertise in key therapeutic areas including Oncology,…